Results 211 to 220 of about 1,021,035 (396)

Anti‐Inflammatory Mechanisms of Selenium Nanosheets in Ulcerative Colitis: Protein Corona, GP130 Interaction, and Transcriptomic Profile

open access: yesAdvanced Science, EarlyView.
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen   +5 more
wiley   +1 more source

Analysis of proinflammatory cytokine responses in Takayasu arteritis. [PDF]

open access: yesArch Rheumatol
Deniz R   +7 more
europepmc   +1 more source

Immunohistochemical studies of proinflammatory cytokines and their receptors in hair follicles of normal human skin.

open access: hybrid, 1996
AA Ahmed   +8 more
openalex   +2 more sources

Oxidized Low-Density Lipoprotein Induces Long-Term Proinflammatory Cytokine Production and Foam Cell Formation via Epigenetic Reprogramming of Monocytes

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2014
S. Bekkering   +5 more
semanticscholar   +1 more source

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

open access: yesAdvanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu   +18 more
wiley   +1 more source

The impact of electronic cigarette smoking on periodontal status and proinflammatory cytokine levels: a cross-sectional study. [PDF]

open access: yesBMC Oral Health
Alnufaiy B   +7 more
europepmc   +1 more source

Targeting Glutamine Metabolism Transporter SLC25A22 Enhances CD8+ T‐Cell Function and Anti‐PD‐1 Therapy Efficacy in Cervical Squamous Cell Carcinoma: Integrated Metabolomics, Transcriptomics and T‐Cell‐Incorporated Tumor Organoid Studies

open access: yesAdvanced Science, EarlyView.
Through metabolomic and transcriptomic analyses, a glutamine‐enriched, immunosuppressive microenvironment is identified in cervical squamous cell carcinoma (CSCC), highlighting the glutamine transporter SLC25A22 as a key regulator of glutamine metabolism, immune checkpoint activation, and CD8+ T‐cell cytotoxicity.
Tingting Ren   +7 more
wiley   +1 more source

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