Results 21 to 30 of about 1,021,035 (396)

IL-21 receptor expression in human tendinopathy [PDF]

, 2014
The pathogenetic mechanisms underlying tendinopathy remain unclear, with much debate as to whether inflammation or degradation has the prominent role.
Campbell, Abigail L., Fazzi, Umberto G., Kerr, Shauna C., Leach, William J., Millar, Neal L., Murrell, George A.C., Reilly, James H., Rooney, Brian P., Smith, Nicola C.   +8 more
core   +2 more sources

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

Nature Communications, 2016
Nrf2 (NF-E2-related factor-2) transcription factor regulates oxidative/xenobiotic stress response and also represses inflammation. However, the mechanisms how Nrf2 alleviates inflammation are still unclear.
E. Kobayashi, Takafumi Suzuki, R. Funayama, Takeshi Nagashima, M. Hayashi, Hiroki Sekine, N. Tanaka, Takashi Moriguchi, H. Motohashi, K. Nakayama, Masayuki Yamamoto   +10 more
semanticscholar   +1 more source

Influence of lipopolysaccharide on proinflammatory gene expression in human corneal, conjunctival and meibomian gland epithelial cells [PDF]

, 2018
PURPOSE: Lipopolysaccharide (LPS), a bacterial endotoxin, is known to stimulate leuokotriene B4 (LTB4) secretion by human corneal (HCECs), conjunctival (HConjECs) and meibomian gland (HMGECs) epithelial cells.
Chen, Di, Darabad, Raheleh Rahimi, Kam, Wendy R., Liu, Yang, Sahin, Afsun, Sullivan, David A.   +5 more
core   +1 more source

Successful Treatment of Granuloma Faciale with Topical Tacrolimus: A Case Report and Immunohistochemical Study

Case Reports in Dermatology, 2012
We report the case of a 55-year-old Japanese patient with granuloma faciale (GF) successfully treated with topical tacrolimus and describe the immunohistochemical study.
Gen-ichi Tojo, Taku Fujimura, Yumi Kambayashi, Katsuko Kikuchi, Setsuya Aiba   +4 more
doaj   +1 more source

Inhibiting USP14 ameliorates inflammatory responses in trophoblast cells by suppressing MAPK/NF‐κB signaling

Immunity, Inflammation and Disease, 2021
Background Preeclampsia can cause severe consequences for pregnant women and infants, and developing effective medicine or methods to prevent or treat patients with preeclampsia is urgently needed.
Yingzi Zhao, Fang Zong
doaj   +1 more source

Inhibition of Ultraviolet B-Induced Expression of the Proinflammatory Cytokines TNF-α and VEGF in the Cornea by Fucoxanthin Treatment in a Rat Model

Marine Drugs, 2016
Ultraviolet B (UVB) irradiation is the most common cause of radiation damage to the eyeball and is a risk factor for human corneal damage. We determined the protective effect of fucoxanthin, which is a carotenoid found in common edible seaweed, on ocular
Shiu-Jau Chen, Ching-Ju Lee, Tzer-Bin Lin, Hsiang-Jui Liu, Shuan-Yu Huang, Jia-Zeng Chen, Kuang-Wen Tseng   +6 more
doaj   +1 more source

α2AP is associated with the development of lupus nephritis through the regulation of plasmin inhibition and inflammatory responses

Immunity, Inflammation and Disease, 2020
Introduction Lupus nephritis (LN) is a common complication of systemic lupus erythematosus (SLE), which is a chronic autoimmune disease. However, the detailed mechanisms underlying this disorder have remained unclear.
Yosuke Kanno, Mei Miyashita, Mariko Seishima, Osamu Matsuo   +3 more
doaj   +1 more source

Proinflammatory cytokines and hemofiltration membranes. [PDF]

Journal of the American Society of Nephrology, 1994
To determine whether the clinical improvement noted in some septic patients undergoing hemofiltration is in part due to the removal of proinflammatory mediators, in vitro hemofiltration of a 1% albumin solution containing recombinant human tumor necrosis factor alpha and interleukin-1 was performed through a variety of hemofilters.
Sasha Goldfarb, Thomas A. Golper
openaire   +3 more sources

Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]

, 2012
BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza, Beloosesky, Ron, Boles, Julie L, Desai, Mina, Ross, Michael G   +4 more
core   +1 more source

Effect of Vitamin D on Peripheral Blood Mononuclear Cells from Patients with Psoriasis Vulgaris and Psoriatic Arthritis. [PDF]

PLoS ONE, 2016
BACKGROUND:Psoriasis, a chronic skin disease with or without joint inflammation, has increased circulating proinflammatory cytokine levels. Vitamin D is involved in calcium homeostasis, bone formation, osteoclastogenesis and osteoclast activity, as well ...
Susana Cubillos, Nadine Krieg, Johannes Norgauer   +2 more
doaj   +1 more source