Results 351 to 360 of about 1,065,082 (380)
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Proinflammatory cytokines mediating burn-injury pain
Pain, 2008Thermal burns induce pain at the site of injury, mechanical hyperalgesia, associated with a complex time-dependent inflammatory response. To determine the contribution of inflammatory mediators to burn injury-induced mechanical hyperalgesia, we measured dynamic changes in the levels of three potent hyperalgesic cytokines, interleukin IL-1 beta, IL-6 ...
Gretchen J, Summer +5 more
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Proinflammatory Plasma Cytokines in Children With Migraine
Pediatric Neurology, 2009Toward understanding the role of cytokines in migraine, this study focused on selected proinflammatory cytokines. The study group consisted of 21 children who had migraine with and without aura; the control group was 24 children with episodic tension-type headache.
Leszek, Boćkowski +2 more
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Proinflammatory Chemical Signaling: Cytokines
2014An increasing body of data has documented altered cytokine concentrations from Parkinson’s disease brains and its rodent models. These changes have been reported in the periphery as well as in the cerebrospinal fluid, where they may be released from a variety of cell types to possibly traffic to and from the brain.
Kumi Nagamoto-Combs, Colin K. Combs
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Leptin as a Proinflammatory Cytokine
2006Leptin is a 16-kDa protein produced mainly by adipocytes. Animal models demonstrate that leptin is required for control of bodyweight and reproduction, since mice defective in leptin or the leptin receptor are obese, hyperphagic insulin resistant and infertile.
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Proinflammatory Cytokines, Aging, and Age-Related Diseases
Journal of the American Medical Directors Association, 2013Inflammation is a physiological process that repairs tissues in response to endogenous or exogenous aggressions. Nevertheless, a chronic state of inflammation may have detrimental consequences. Aging is associated with increased levels of circulating cytokines and proinflammatory markers.
M. Michaud +7 more
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Proinflammatory Cytokine Inhibition of Lacrimal Gland Secretion
Cornea, 2000A decrease in lacrimal and salivary gland secretion is a primary cause of dry eye and dry mouth. Sjogren’s syndrome is the leading cause of the aqueous tear deficient type of dry eye.1-3 It is an autoimmune disease, which occurs almost exclusively in females (>90), and involves an extensive lymphocytic infiltration of the lacrimal and salivary glands ...
Claire Larkin, Kublin +2 more
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Proinflammatory cytokines in cervicogenic headache.
Functional neurology, 1999Interleukin-1 beta (IL-1 beta) and Tumour Necrosis Factor-alpha (TNF-alpha) exert their multifunctional biological effect by promoting and increasing the molecular events of cellular inflammation. The aim of this study was to find out whether the cytokine pattern of cervicogenic headache (CH) patients tends, like that seen in cluster headache, towards ...
MARTELLETTI, Paolo +2 more
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Proinflammatory Cytokines and Treatment of Disease
Annals of the New York Academy of Sciences, 1998ABSTRACT: Bacterial infections in the immunocompromised host cause considerable mortality, and even recently developed antimicrobial strategies often fail to cure these infections, especially in granulocytopenic patients. Cytokines and hematopoietic growth factors have been shown to stimulate host defense mechanisms in vitro and in vivo.
Meer, J.W.M. van der +3 more
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Regulation of autoimmunity by proinflammatory cytokines
Current Opinion in Immunology, 1998Studies extending over a decade have provided compelling evidence to suggest that chronic expression of proinflammatory cytokines in vivo leads to unique regulatory properties that target the cognate immune response in a way that appears to be beneficial to the host.
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