Results 191 to 200 of about 5,465,036 (281)

Acute Intoxication With Alcohol Reduces Trauma-Induced Proinflammatory Response and Barrier Breakdown in the Lung via the Wnt/β-Catenin Signaling Pathway. [PDF]

Front Immunol, 2022
Noack L, Bundkirchen K, Xu B, Gylstorff S, Zhou Y, Köhler K, Jantaree P, Neunaber C, Nowak AJ, Relja B.   +9 more
europepmc   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Piezo1 restrains proinflammatory response but is essential in T-cell-mediated immunopathology. [PDF]

J Leukoc Biol
Choi SH, Santin A, Myers JT, Kim BG, Eid S, Tomchuck SL, Kingsley DT, Huang AY.   +7 more
europepmc   +1 more source

The Acute Hepatic NF-κB-Mediated Proinflammatory Response to Endotoxemia Is Attenuated in Intrauterine Growth-Restricted Newborn Mice. [PDF]

Front Immunol, 2021
Zarate MA, De Dios RK, Balasubramaniyan D, Zheng L, Sherlock LG, Rozance PJ, Wright CJ.   +6 more
europepmc   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

TIM4+macrophages suppress the proinflammatory response to maintain the chronic alveolar echinococcosis infection. [PDF]

Front Cell Infect Microbiol
Wang L, Liu Y, Ma Y, Zhou X, Aibibula M, Zhang X, Zhao H, Zhou J, Tian F, Ma X.   +9 more
europepmc   +1 more source

Emergency response program

, 2019
"February 2019."Requirements for reporting petroleum-related spills -- What happens when I call Ohio EPA's spill hotline? -- Who is responsible for spill cleanup?

core  

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

TFEB-mediated proinflammatory response in murine macrophages induced by acute Alpha7 nicotinic receptor activation. [PDF]

J Leukoc Biol
Honwad HH, Najibi M, Shen J, Watts S, Fu AM, Koscso B, Bogunovic M, Irazoqui JE.   +7 more
europepmc   +1 more source

Macrophages augment the skeletal muscle proinflammatory response through TNFα following LPS-induced acute lung injury. [PDF]

FASEB J, 2021
Bivona JJ, Crymble HM, Guigni BA, Stapleton RD, Files DC, Toth MJ, Poynter ME, Suratt BT.   +7 more
europepmc   +1 more source