Results 61 to 70 of about 15,819,940 (362)
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Identify and Report Water Pollution: An Interpretive Guide to Surface Water Conditions of the New Hampshire Coastal Watershed [PDF]
, 2007 This guide was designed to help people who work or recreate outdoors to interpret surface water conditions so that they would recognize a pollution incident and know how to report it.
New Hampshire Estuaries Project
core +6 more sources
Russian Language Studies, 2019 The relevance of the research is justified by the necessity of developing methodical basis for project-research activity at the lessons of the Russian language at schools.
Margarita I. Vasilieva
doaj +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Journal of Cheminformatics, 2019 This paper describes the 10 years of work and research results of the chemfp project, available from http://chemfp.com/ . The project started as a way to promote the FPS format for cheminformatics fingerprint exchange. This is a line-oriented text format meant to be easy to read and write.
openaire +4 more sources
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
World Nutrition, 2017 Subject to more discussion and appeal, the evidence is that modern conventional nutrition, focused on human biochemistry and physical health, is a mistake. Nutrition needs to face the facts of this century, and so to fly – thus, the phoenix.
The Project Phoenix team
doaj
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Forum Bibliotek Medycznych, 2020 The purpose of this article is to discuss a three-year project implemented by the Main Library of the Medical University of Warsaw as part of the project of the Ministry of Science and Higher Education for the dissemination of science (DUN).
Elżbieta Maria Walczuk
doaj +1 more source