Results 181 to 190 of about 21,342,775 (312)

Random Projections with Control Variates

Proceedings of the 6th International Conference on Pattern Recognition Applications and Methods, 2017
Keegan Kang, Giles Hooker
openaire   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

<i>HLA-DRB1*14</i> is associated with lower odds of symptomatic SARS-CoV-2 infection in Mexican individuals. [PDF]

Front Immunol
Hernández EG, Daza-Mendoza DA, González-Rivas E, Serrano-Vázquez A, Pérez-Juárez H, Uribe-García A, Rostro-Alonso GO, Morán-Silva P, Rojas-Velázquez L, Ximénez García C.   +9 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Correction: Integrated histopathology and single-cell transcriptomics reveal distinct pathological features and foamy macrophage characteristics in spinal tuberculosis and brucellar spondylitis. [PDF]

Front Immunol
Liu Q, Guo H, Liu J, Tao Z, Ma L, Gu Z, Yue X, Wei D, Niu N, Shi J, Yang Z.   +10 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

TUBERCULOSIS CONTROL CONCEPT IN NEPAL

Journal of Nepal Medical Association, 2003
Jaya N Giri, D H Patterson
doaj   +1 more source

Early insulin initiation in type 2 diabetes: efficacy, safety, and clinical implications: a systematic review with narrative synthesis. [PDF]

Front Endocrinol (Lausanne)
Albasheer O, Mohamed AH, Abdalghani N, Hamdi A, Ayish DAM, Ayish F, Alssum A, Maashi AY, El Hassan LAM, Madkhali T, Muqri M, Awaf AA, Alessa H, Madkhali A, Hakami A.   +14 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Reflections on the Application of Aboriginal Community Controlled Health Organisations' Research Principles in a Photovoice Food Security Study. [PDF]

Health Promot J Austr
Chappell EL, Ferguson M, Brimblecombe J, Hefler M, Deen C, Chan E, Stubbs E, Cadet-James Y.   +7 more
europepmc   +1 more source