Results 81 to 90 of about 13,048,775 (285)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

COMMUNICATION STRATEGIES AND MECHANISMS OF PUBLIC MANAGEMENT OF COAL COMMUNITIES IN THE CONDITIONS OF MODERN CHALLENGES

Baltic Journal of Economic Studies
The article is devoted to the study of communication strategies and mechanisms of public governance of coal communities in the face of modern challenges through the analysis of new approaches to public administration. The subject of the present study is
Liubov Kvasnii, Svyatoslav Kostyuk, Nataliia Voitovych   +2 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Explorative R&D collaboration: Searching for effective and efficient governance mechanisms. [PDF]

Explorative R&D collaboration is an important alternative for the internal development of new technologies. The high failure rate of this type of inter-organizational collaboration, however, indicates that governing explorative R&D collaboration is not a
Janssens, Maddy, Bouwen, René, Van Looy, Bart, Faems, Dries   +3 more
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Governance, contracts, and culture: A triadic approach to megaproject performance

Project Leadership and Society
Despite their transformative ambitions, transport megaprojects, such as high-speed rail systems, often underperform. This study investigates the California High-Speed Rail Project (CAHSRP) using a critical realist methodology and a Context-Mechanism ...
Jackson Sekasi, Steven Harrod, Victor Andrade   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Assessing the role of territorial governance in the success of territory projects: A case study of the Fez craft industry

Moroccan Journal of Quantitative and Qualitative Research
Territorial governance has become omnipresent in all economic, political or social discourses, it is a question of implementing dynamic processes of coordination, pooling efforts, shared visions of different actors of a territory and diverse resources ...
saarra boutahar, Bouchra Debbagh
doaj   +1 more source

Asymmetric collaborative governance in Indonesia’s new capital: A quasi–public–private partnership approach to regional financial institution engagement [PDF]

International Journal of Human Capital in Urban Management
BACKGROUND AND OBJECTIVES: This study examined the implementation of the BPD Kaltimtara headquarters project in Indonesia’s New Capital City (Ibu Kota Nusantara/IKN) as a pioneering quasi-public-private partnership (quasi-PPP) model.
E. Maradona, B. Ngarawula, T. Hariyanto
doaj   +1 more source