Results 81 to 90 of about 3,762,405 (302)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Maleku: an evolutionary visual software analytics tool for providing insights into software evolution [PDF]
, 2011 Software maintenance is a complex process that requires the understanding and comprehension of software project details. It involves the understanding of the evolution of the software project, hundreds of software components and the relationships among ...
García-Peñalvo, Francisco +4 more
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Towards a situated media practice: Reflections on the implementation of project-led problem-based learning [PDF]
, 2013 In the field of media practice education, project-based learning is utilized as a major pedagogic paradigm with the aim of mirroring professional practice within the curriculum.
Hanney, Roy
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
BuildingsThe 2015 Nepal Earthquake (Mw7.8) affected more than 9000 schools in the country. Damage distribution in the 14 most-affected administrative districts shows that the construction practices were an important determent for the level of damage extended. The
Youb Raj Paudyal, Netra Prakash Bhandary
doaj +1 more source
A Learning Perspective on Groupware Implementation [PDF]
, 2001 We propose to look at the implementation of groupware from a learning perspective. In this paper we motivate this view and outline our research model.
Bondarouk, Tatyana, Sikkel, Klaas
core +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
THE LAST PLANNER® SYSTEM PATH CLEARING APPROACH IN ACTION: A CASE STUDY [PDF]
, 2018 The “Last Planner® System” (LPS) is commonly viewed as the foundation of Lean Project Delivery. It is increasingly used in certain parts of the globe.
Daniel, Emmanuel +2 more
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source