Results 61 to 70 of about 5,104,399 (355)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Lessons learnt from the use of relationship-based procurement methods in Australia: clients’ perspectives

Construction Economics and Building, 2016
This paper aims to review the use of various construction procurement systems and present the development of Relationship-Based Procurement (RBP) Methods currently in use within the Australian construction industry.
Farshid Rahmani, Malik M A Khalfan, Tayyab Maqsood   +2 more
doaj   +1 more source

Project management

, 2018
The main aim of this chapter is to present the essential concepts of project management, including a definition of the concept of a project, a brief history of project management, a general vision of the differentmethodologies used in the field, and some insights on present trends in the field.
Calleja Sanz, Gema, Olivella Nadal, Jordi, Vinyals Robert, Juan   +2 more
openaire   +3 more sources

Project management and music in education and related fields [PDF]

, 2015
Project Management (PM) is a well-established field of research with the scope of inquiry now ranging far beyond the industrial and corporate sectors from which it first emerged.
Sivaraman, R, Wilson, Chris
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Income Analysis of Seasonal Targeted Shark Fishers in Muncar, Banyuwangi, Indonesia [PDF]

BIO Web of Conferences
Shark fisheries hold significant economic importance for coastal populations, especially in areas where alternative livelihoods are scarce. In Muncar, East Java, shark fishing has historically contributed to both income generation and food security among
Osmaleli Osmaleli, Salim Muhammad, Rizka Antika, Tawang Firmansyah, Larasati Chindy, Fadloli Ahmad, Rizal Hasan, Irianies Gozali, Adrianto Luky, Kusumastanto Tridoyo, Yulianto Gatot, Booth Hollie   +11 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Classroom expriments on project management communication [PDF]

, 2015
This manuscript gives a brief overview of three sets of experiments in the classroom with students following a Project Management (PM) course module using a blended learning approach.
Vanhoucke, Mario, Wauters, Mathieu
core   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source