Results 61 to 70 of about 65,819 (256)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Analysis of Scheduling Method in Building Projects: A Case of Line of Balance and Precedence Diagram Method

Media Komunikasi Teknik Sipil
The construction industry plays a significant role in a country's economic growth. However, construction projects frequently face challenges in meeting schedule targets. Project scheduling is crucial as it provides insights into enhancing the development
Rosmariani Arifuddin, Andi Nurul Fatimah, Muh Rifan Fadlillah   +2 more
doaj   +1 more source

A solution procedure for preemptive multi-mode project scheduling problem with mode changeability to resumption

Applied Computing and Informatics, 2018
Extensive research has been devoted to the multi-mode resource constrained project scheduling problem (MRCPSP). However, little attention has been paid to problems where preemption is allowed.
Behrouz Afshar-Nadjafi
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Fuzzy goal programming approach for multi-objective multi-mode resource constrained project scheduling problem

KKU Engineering Journal, 2014
This research proposes fuzzy goal programming model for multi-objective multi-mode resource constrained project scheduling problem. Objectives of the problem are minimization of the total time and the total cost of the project.
Busaba Phruksaphanrat, Saran Jarernsuk
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Optimasi Biaya dan Waktu dalam Penyusunan Jadwal Pelaksanaan Proyek (Studi Kasus Proyek Pembangunan Gedung Pusat Kegiatan Mahasiswa Universitas Diponegoro Semarang)

Media Komunikasi Teknik Sipil, 2015
Execution of conctruction project executed to pass selected project management system from planning phase until operation phase. Unfavorable scheduling system can cause the project to be inefficient.
Dadiyono Amat Pawiro
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Software Project Scheduling Problem: A Review

مهندسی مخابرات جنوب
The software project scheduling problem (SPSP) is one of the most important activities in software project development. One of the main reasons for unsuccessful software project completion is non-compliance with cost and schedule plans, often due to ...
Javad Pashaei Barbin, Mahdi Jalali
doaj  

Triple-Layer Genetic Algorithm (3LGA) for Project Scheduling and Material Ordering Problem with Limited Storage Space

Buildings
Efficient project management in the construction industry depends on optimizing project scheduling and material ordering, two interdependent processes that significantly impact both costs and durations.
Suphawut Malaikrisanachalee, Narongrit Wongwai, Pongpan Promchun   +2 more
doaj   +1 more source