Results 71 to 80 of about 66,578 (256)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

INTEGRATING RISK MANAGEMENT INTO PROJECT SCHEDULING: A CRITICAL PATH METHOD APPROACH IN COAL MINING DEVELOPMENT PROJECT

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This study analyses the integration of risk management into project scheduling in a coal mining development project. A mixed-methods case study was applied, combining interviews, observations, document analysis, and structured questionnaires.
Bayu Setiyawan, Siti Nursyamsiah
doaj   +1 more source

Scheduling of Empennage Structure Design Project of Indonesia’s Aircraft with Critical Path Method (CPM)

open access: yesMATEC Web of Conferences, 2018
Production of the aircraft becomes very important to facilitate many passengers of aircraft in Indonesia in the future. The design of a very complex aircraft requires proper project management.
Wulandari Arin, Dachyar M., Farizal
doaj   +1 more source

Analisis Tingkat Kepuasan Konsumen terhadap Pelayanan Bongkar-Muat Barang pada Terminal Petikemas Semarang

open access: yesMedia Komunikasi Teknik Sipil, 2015
This study aims to analyze the level of consumer expectations and service performance and user satisfaction level loading service at Semarang Container Terminal.
Yoeli Janto
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Mathematical formalization of project scheduling problems

open access: yesТруды Института системного программирования РАН, 2018
Theory of scheduling and project planning is widely applied in diverse scientific and industrial areas. To effectively solve application-specific problems it is necessary to take into account a lot of factors such as task execution models, precedence ...
A. S. Anichkin, V. A. Semenov
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Multi-Project Scheduling with Uncertainty and Resource Flexibility: A Narrative Review and Exploration of Future Landscapes

open access: yesAlgorithms
This paper presents a narrative review on the Resource-Constrained Multi-Project Scheduling Problem (RCMPSP) under uncertainty and resource flexibility.
Marzieh Aghileh   +3 more
doaj   +1 more source

Using Fuzzy Clustering Chaotic-based Differential Evolution to solve multiple resources leveling in the multiple projects scheduling prob

open access: yesAlexandria Engineering Journal, 2016
Project scheduling is an important part of construction project planning. Resource leveling is the process used within project scheduling to reduce fluctuations in resource usage over the period of project implementation.
Duc-Hoc Tran   +2 more
doaj   +1 more source

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