Results 71 to 80 of about 524,960 (300)
Project scheduling is essential to be planned before activities. Standard methods of project scheduling based on precedence constraints scheduling events and the assumption that resources are not unlimited capacity.
Maria Krisnawati
doaj
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
In collaborative product development project plan phase, a reasonable allocation plan can shorten project duration. Static scheduling is a useful way to obtain the allocation result.
Yingzi Li, Shuo Zhang
doaj +1 more source
Solution and quality robust project scheduling: a methodological framework. [PDF]
The vast majority of the research efforts in project scheduling over the past several years has concentrated on the development of exact and suboptimal procedures for the generation of a baseline schedule assuming complete information and a deterministic
Herroelen, Willy, Leus, Roel
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
A plant construction project always involves lots of activities. Precise information about the activities duration is unfortunately unavailable due to the uncertain resources capacity.
Hsian Jong Hsiau, Chun Wei R. Lin
doaj +1 more source
A multi-agent system with application in project scheduling [PDF]
The new economic and social dynamics increase project complexity and makes scheduling problems more difficult, therefore scheduling requires more versatile solutions as Multi Agent Systems (MAS).
Constanța Nicoleta BODEA +2 more
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
CONTRIBUTIONS TO MULTI-AGENT SYSTEMS IMPLEMENTATION FOR PROJECT SCHEDULING [PDF]
Increasing project complexity makes scheduling problems more difficult to solve and requires more versatile algorithms. Two different approaches for the project scheduling optimization could be considered: TCPSP (Time-Constrained Project Scheduling), and
Constanta Nicoleta BODEA +1 more
core

