Results 101 to 110 of about 899,437 (254)
Projection in Arabic: a typological overview
This article examines the different aspects of projection by focusing on the processes construing this area of the lexicogrammar. It also explores how Arabic construes this dimension of the lexicogrammar across the rank scale and beyond.
Bardi Mohamed Ali
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Background Musculoskeletal (MSK) disorders are a leading cause of disability worldwide, particularly prevalent among women of childbearing age (WCBA). Our aim is to comprehensively assess the global, regional, and national burden of MSK disorders in WCBA,
Liang Luo +5 more
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The Ends of Things Show Disc 01 [Projection]
The Theatre and Dance Platform holds a digital copy (MP4) of a video on Mini DV in the Lucy Guerin Inc collection.Projection for Lucy Guerin's The Ends of Things. Projection comprises eleven sections: 1. Colour Bars and Test Tone (0:52); 2.
Lucy Guerin Inc
core
Assessing and projecting the global impacts of Alzheimer’s disease
BackgroundThis study aims to assess the global burden of Alzheimer’s disease (AD) from 1990 to 2030, with a focus on incidence, mortality, and disability-adjusted life years (DALY).MethodsData on the incidence rates, DALY rates, and death rates of AD ...
Nanlong Zhang, Shuren Chai, Jixing Wang
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Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
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Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source

