Results 61 to 70 of about 534,426 (265)
The MAJORANA Project
Journal of Physics: Conference Series, 2009 Building a \BBz experiment with the ability to probe neutrino mass in the inverted hierarchy region requires the combination of a large detector mass sensitive to \BBz, on the order of 1-tonne, and unprecedented background levels, on the order of or less than 1 count per year in the \BBz signal region. The MAJORANA Collaboration proposes a design based Varner, R.L., Schubert, A.G., Bertrand, F.E., Shirchenko, M., Farmer, T., Johnson, R.A., Myers, A.W., Yin, Z.-B., Hossbach, T., Finnerty, P., Ejiri, H., Akashi-Ronquest, M., Howe, M.A., Marino, M.G., Efremenko, Yu., Boswell, M., Vetter, K., Doe, P.J., Guiseppe, V.E., Wouters, J.M., Miley, H.S., Fast, J., Nomachi, M., Elliott, S.R., Hoppe, E., Chan, Y.-D., Amsbaugh, J.F., Greenberg, C., Dunmore, J.A., Kidd, M., Burritt, T.H., Tornow, W., Barbeau, P., Wilkerson, J.F., Timkin, V., Kephart, J., Hallin, L., Amman, M., Orrell, J., Shima, T., Fujikawa, B., Hurley, D., Bugg, W., Egorov, V., Keller, C., Odom, B., MacMullin, S., Gusey, K., Cianciolo, T.V., Hazama, R., Creswick, R., Luke, P., Barabash, A.S., Aalseth, C.E., Vanyushin, I., Yakushev, E., Leviner, L., Detwiler, J.A., Collar, J., Kouzes, R.T., Yu, C.-H., Kochetov, O., Rykaczewski, K.P., Tull, C., Robertson, R.G.H., Keillor, M., Back, H.O., Farach, H., McDonald, A.B., Young, A.R., Ely, J., Bergevin, M., Hime, A., Warner, R., Rodriguez, L., Thompson, R., Poon, A.W.P., Baktash, C., Cromaz, M., Konovalov, S.I., Radford, D.C., Van Wechel, T.D., Hyronimus, B., Mei, D.-M., Riley, N., Esterline, J., Rielage, K., Henning, R., Avignone, F.T., III, Beene, J.R., Gehman, V.M., Brudanin, V., Prior, G., Reeves, J.H., Yumatov, V., Lesko, K.T. +95 moreopenaire +2 more sourcesTracking Health Related Quality of Life From Diagnosis to Follow‐Up Among Australian Children With Acute Lymphoblastic Leukaemia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.Clare Ghows, Clarissa E. Schilstra, Karen McCleary, Nancy E. Briggs, Rishi S. Kotecha, Richard De Abreu Lourenco, Shanti Ramachandran, Ruelleyn Cockcroft, Rachel Conyers, Siobhan Cross, Luciano Dalla‐Pozza, Peter Downie, Tamas Revesz, Michael Osborn, Frank Alvaro, Claire E. Wakefield, Glenn M. Marshall, Toby Trahair, Marion K. Mateos, Joanna E. Fardell +19 morewiley +1 more sourceClinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer
Pediatric Blood &Cancer, EarlyView.ABSTRACT
A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and Thomas R. W. Oliver, Dyanne Rampling, Barbara Walkowiak, Nathaniel D. Anderson, Manas Dave, Henry Lee‐Six, Sadie Baskind, Pooja Balasubramanian, Glenn Anderson, Conor Parks, Toochi Ogbonnah, Emilia R. Robertson, Simon Hannam, Rohan Verma, John C. Achermann, Liina Palm, Neil Sebire, Thomas Jacques, Tom Watson, Carryl Dryden, Karin Straathof, Mette Jorgensen, Olga Slater, Sam Behjati, Sarita Depani, J. Ciaran Hutchinson +25 morewiley +1 more sourceClimate change impacts the epidemic of dysentery: determining climate risk window, modeling and projection
Environmental Research Letters, 2019 Dysentery, an acute infectious disease still prevalent in many parts of the world, especially in developing counties, is caused by a group of bacteria known as Shigella . Because of the sensitivity of dysentery to climate change, the relationship between Chenlu Li, Xiaoxu Wu, Duoying Ji, Jianing Liu, Jie Yin, Zhiyi Guo +5 moredoaj +1 more sourceImmunoglobulin Depletion and Recovery Following Blinatumomab in Infants With KMT2A‐Rearranged ALL
Pediatric Blood &Cancer, EarlyView.ABSTRACT
Adding blinatumomab to standard chemotherapy for infants with KMT2A‐rearranged acute B‐cell lymphoblastic leukemia (KMT2A‐r B‐ALL) improves outcomes. Although blinatumomab impairs immunoglobulin G (lgG) production, increasing infection susceptibility, IgG recovery remains poorly understood.Miguel Vieira Martins, Paola de Lorenzo, Rishi S. Kotecha, Andishe Attarbaschi, Gabriele Escherich, Karsten Nysom, Jan Stary, Alina Ferster, Benoit Brethon, Franco Locatelli, Martin Schrappe, Peggy E. Scholte‐van Houtem, Maria G. Valsecchi, Rob Pieters, Inge M. van der Sluis +14 morewiley +1 more sourcePancreatic cancer mortality trends attributable to high fasting blood sugar over the period 1990–2019 and projections up to 2040
Frontiers in EndocrinologyBackgroundPancreatic cancer (PC) is a prevalent malignancy within the digestive system, with diabetes recognized as one of its well-established risk factors.MethodsData on PC mortality attributed to high fasting blood sugar were retrieved from the Global Yongguang Wei, Yongguang Wei, Yongguang Wei, Zedong Qin, Xiwen Liao, Xiwen Liao, Xiwen Liao, Xin Zhou, Xin Zhou, Xin Zhou, Huasheng Huang, Huasheng Huang, Huasheng Huang, Chenlu Lan, Chenlu Lan, Chenlu Lan, Wei Qin, Wei Qin, Wei Qin, Guangzhi Zhu, Guangzhi Zhu, Guangzhi Zhu, Hao Su, Hao Su, Hao Su, Tao Peng, Tao Peng, Tao Peng +27 moredoaj +1 more sourceForecasting Head and Neck Cancer Trends in GCC Countries: Implications for Public Health Policy and Strategy
Risk Management and Healthcare Policy, 2023 Alla Alsharif,1,* Maha T Alsharif,2,* Meyassara Samman,3,* Nada Binmadi,2,* Saba Kassim,1,* Samah Mourad,4,* Saman Warnakulasuriya5,6,* 1Department of Preventive Dental Sciences, Taibah University Dental College & Hospital, Al-Alsharif A, Alsharif MT, Samman M, Binmadi N, Kassim S, Mourad S, Warnakulasuriya S +6 moredoaj The SpiNNaker Project
Proceedings of the IEEE, 2014 The spiking neural network architecture (SpiNNaker) project aims to deliver a massively parallel million-core computer whose interconnect architecture is inspired by the connectivity characteristics of the mammalian brain, and which is suited to the modeling of large-scale spiking neural networks in biological real time.Steve B. Furber, Francesco Galluppi, Steve Temple, Luis A. Plana +3 moreopenaire +1 more sourceAdmixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium +24 morewiley +1 more source
