Results 51 to 60 of about 426,008 (281)
Exploratory Projection Pursuit [PDF]
Journal of the American Statistical Association, 1985 Abstract A new projection pursuit algorithm for exploring multivariate data is presented that has both statistical and computational advantages over previous methods. A number of practical issues concerning its application are addressed. A connection to multivariate density estimation is established, and its properties are investigated through ...
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Projection pursuit in high dimensions
, 2022 Projection pursuit is a multivariate statistical technique aimed at finding interesting data projections. It suffers from several problems when applied to high-dimensional datasets.
Nicola Loperfido
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A new result on recovery sparse signals using orthogonal matching pursuit
Statistical Theory and Related Fields, 2022 Orthogonal matching pursuit (OMP) algorithm is a classical greedy algorithm widely used in compressed sensing. In this paper, by exploiting the Wielandt inequality and some properties of orthogonal projection matrix, we obtained a new number of ...
Xueping Chen +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Projection pursuit for exploratory supervised classification [PDF]
, 2005 In high-dimensional data, one often seeks a few interesting low-dimensional projections that reveal important features of the data. Projection pursuit is a procedure for searching high-dimensional data for interesting low-dimensional projections via the ...
Cook, Dianne +3 more
core +1 more source
Hardware Trojans detection based on projection pursuit
Tongxin xuebao, 2013 A novel hardware Trojans detection technique using the side channel signals of chips was proposed.Based on the projection pursuit with absolute information divergence index,this technique could find out the data structure enables reflect high dimension ...
Peng ZHANG, Xin-cheng WANG, Qing ZHOU
doaj +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source