Results 51 to 60 of about 10,982 (282)

3D CIRCULAR HISTOGRAM

open access: yesPesquimat, 2014
This paper aims to present a new tool for statistically exploring of multidimensional data called 3D Circular Histogram. Unlike classical histogram based on Cartesian coordinates, what is shown here is constructed from a polar coordinate system and the ...
Erwin Kraenau Espinal
doaj   +1 more source

Assessment of Waterlogging Risk in the Deep Foundation Pit Projects Based on Projection Pursuit Model

open access: yesAdvances in Civil Engineering, 2020
As a result of global climate change and urbanization, waterlogging disasters have occurred frequently around the world, and deep foundation pit projects with lower terrain suffer even more.
Han Wu, Junwu Wang
doaj   +1 more source

Projection pursuit for exploratory supervised classification [PDF]

open access: yes, 2005
In high-dimensional data, one often seeks a few interesting low-dimensional projections that reveal important features of the data. Projection pursuit is a procedure for searching high-dimensional data for interesting low-dimensional projections via the ...
Cook, Dianne   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Targeted Projection Pursuit Tool for Gene Expression Visualisation

open access: yesJournal of Integrative Bioinformatics, 2006
A tool is introduced that uses a novel technique to enable users to explore two-dimensional views of high dimensional gene expression data sets. Unlike other such tools, the interface is intuitive and efficient, allowing the user to easily select views ...
Faith Joe, Brockway Michael
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A new result on recovery sparse signals using orthogonal matching pursuit

open access: yesStatistical Theory and Related Fields, 2022
Orthogonal matching pursuit (OMP) algorithm is a classical greedy algorithm widely used in compressed sensing. In this paper, by exploiting the Wielandt inequality and some properties of orthogonal projection matrix, we obtained a new number of ...
Xueping Chen   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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