Results 101 to 110 of about 2,066,066 (332)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

The Rostromedial Tegmental Nucleus: Anatomical Studies and Roles in Sleep and Substance Addictions in Rats and Mice

open access: yesNature and Science of Sleep, 2020
Ya-Nan Zhao,1,* Yu-Dong Yan,1,* Chen-Yao Wang,1 Wei-Min Qu,1 Thomas C Jhou,2 Zhi-Li Huang,1 Su-Rong Yang1 1Department of Pharmacology, School of Basic Medical Sciences, Fudan University, Shanghai, People’s Republic of China; 2Department of ...
Zhao YN   +6 more
doaj  

Contractive projections and operator spaces

open access: yes, 2002
Parallel to the study of finite dimensional Banach spaces, there is a growing interest in the corresponding local theory of operator spaces. We define a family of Hilbertian operator spaces H_n^k,0< k < n+1, generalizing the row and column Hilbert spaces
Neal, Matthew, Russo, Bernard
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Alaska Fuel Price Projections 2014-2040 [PDF]

open access: yes, 2014
The Alaska Fuel Price Projections are developed annually for the Alaska Energy Authority (AEA) for the purpose of estimating the potential costs and benefits of renewable energy projects.
Fay, Ginny   +1 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A non-injective version of Wigner's theorem

open access: yes, 2018
Let $H$ be a complex Hilbert space and let ${\mathcal F}_{s}(H)$ be the real vector space formed by all self-adjoint finite rank operators on $H$. We prove the following non-injective version of Wigner's theorem: every linear operator on ${\mathcal F}_{s}
Pankov, Mark, Plevnik, Lucijan
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Prospects for global food security: a critical appraisal of past projections and predictions [PDF]

open access: yes
During the last half century, a number of individuals and institutions, including the Food and Agriculture Organization of the United Nations (FAO) and IFPRI, have engaged in projections of future food demand, supply, and related variables. In this brief,
McCalla, Alex F, Revoredo, Cesar L.
core  

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