Results 101 to 110 of about 365,712 (267)

THE RESEARCH OF USING «THE COST RECOVERY» METHOD IN THE COST MANAGEMENT

open access: yesВестник университета, 2019
The article is about «Cost recovery» method. It is considered how the method can be used in the various types of tasks (the account, planning, forecasting, rationing, optimization, etc.).
Y. Vorontsova, I. Barakhanova
doaj  

Identification of a Hippocampus‐to‐Zona Incerta Projection involved in Motor Learning

open access: yesAdvanced Science
Motor learning (ML), which plays a fundamental role in growth and physical rehabilitation, involves different stages of learning and memory processes through different brain regions.
Zhuo‐Hang Zhang   +14 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Causes of Increased Compound Temperature and Precipitation Extreme Events in the Arid Region of Northwest China from 1961 to 2100

open access: yesRemote Sensing
Compound extreme events pose more grave threats to human health, the natural environment, and socioeconomic systems than do individual extreme events. However, the drivers and spatiotemporal change characteristics of compound extreme events under climate
Huihui Niu   +8 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Projection of populations by level of educational attainment, age, and sex for 120 countries for 2005-2050

open access: yesDemographic Research, 2010
Using demographic multi-state, cohort-component methods, we produce projections for 120 countries (covering 93Š of the world population in 2005) by five-year age groups, sex, and four levels of educational attainment for the years 2005-2050. Taking
Samir KC   +4 more
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

TEACHING DESCRIPTIVE GEOMETRY – CONSTRUCTING AND DEVELOPING THE SURFACES OF SOLIDS

open access: yesJournal of Industrial Design and Engineering Graphics, 2019
The paper presents applications developed for teaching descriptive geometry – representation of solids and development of the surface of the solids. The purpose of the applications presented is to enable the development and improvement of the spatial ...
Ramona Clinciu
doaj  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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