Results 111 to 120 of about 2,066,066 (332)

U.S. Population Projections: 2005-2050 [PDF]

open access: yes, 2008
Projects population growth, new immigrants and their descendants as a percentage of that growth, and changes in the population's ethnic/racial composition.
D'Vera Cohn, Jeffrey S. Passel
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

World Urbanization Prospects: an alternative to the UN model of projection compatible with the mobility transition theory

open access: yesDemographic Research, 2005
This paper proposes to critically examine the United Nations projections on urbanisation. Both the estimates of current trends based on national data and the method of projection are evaluated.
Philippe Bocquier
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A new model for global glacier change and sea-level rise

open access: yesFrontiers in Earth Science, 2015
The anticipated retreat of glaciers around the globe will pose far-reaching challenges to the management of fresh water resources and significantly contribute to sea-level rise within the coming decades.
Matthias eHuss   +3 more
doaj   +1 more source

Non-commutative residue of projections in Boutet de Monvel's calculus

open access: yes, 2007
Using results by Melo, Nest, Schick, and Schrohe on the K-theory of Boutet de Monvel's calculus of boundary value problems, we show that the non-commutative residue introduced by Fedosov, Golse, Leichtnam, and Schrohe vanishes on projections in the ...
Gaarde, Anders
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Principal angles and approximation for quaternionic projections

open access: yes, 2013
We extend Jordan's notion of principal angles to work for two subspaces of quaternionic space, and so have a method to analyze two orthogonal projections in M_n(A) for A the real, complex or quaternionic field (or skew field).
Loring, Terry A.
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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