Results 21 to 30 of about 353,264 (267)

Pharmacokinetic and Pharmacodynamic Effects of Oral CXA‐10, a Nitro Fatty Acid, After Single and Multiple Ascending Doses in Healthy and Obese Subjects

Clinical and Translational Science, 2019
10‐nitro‐9(E)‐octadec‐9‐enoic acid (CXA‐10), a novel nitro fatty acid compound, demonstrates potential as a therapeutic agent in multiple disease indications in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play ...
Rachel M. Garner, Diane R. Mould, Carla Chieffo, Diane K. Jorkasky   +3 more
doaj   +1 more source

Projected changes in mean climate and extremes from downscaled high-resolution CMIP6 simulations in Australia

Weather and Climate Extremes
High-resolution climate change projections are required to evaluate local and regional climate change impacts. We used CCAM (Conformal Cubic Atmospheric Model) to dynamically downscale CMIP6 GCMs (Global Climate Models) over Australia under three ...
Sarah Chapman, Jozef Syktus, Ralph Trancoso, Nathan Toombs, Rohan Eccles   +4 more
doaj   +1 more source

Optogenetic stimulation of Kiss1ARC terminals in the AVPV induces surge-like luteinizing hormone secretion via glutamate release in mice

Frontiers in Endocrinology, 2022
Kisspeptin neurons are mainly located in the arcuate (Kiss1ARC, vis-à-vis the GnRH pulse generator) and anteroventral periventricular nucleus (Kiss1AVPV, vis-à-vis the GnRH surge generator).
Xi Shen, Xi Shen, Yali Liu, Xiao Feng Li, Hui Long, Li Wang, Qifeng Lyu, Yanping Kuang, Kevin T. O’Byrne   +8 more
doaj   +1 more source

Evaluating Knowledge Gaps in Sea‐Level Rise Assessments From the United States

Earth's Future, 2023
There have been many scientific advances regarding future sea‐level projections, however it is unclear if these have been transferred to assessment reports used by stakeholders.
Andra J. Garner, Sarah E. Sosa, Fangyi Tan, Christabel Wan Jie Tan, Gregory G. Garner, Benjamin P. Horton   +5 more
doaj   +1 more source

Frameworks to envision equitable urban futures in a changing climate: A multi-level, multidisciplinary case study of New York City

Frontiers in Built Environment, 2022
Cities are at the forefront of climate change action and planning for futures that are concomitantly more resilient and equitable, making local goals imperative for global sustainability. Under the multiple challenges of changing climatic, ecological and
Deborah Balk, Deborah Balk, Daniela Tagtachian, Daniela Tagtachian, Leiwen Jiang, Leiwen Jiang, Peter Marcotullio, Elizabeth M. Cook, Bryan Jones, Bryan Jones, Ahmed Mustafa, Timon McPhearson, Timon McPhearson, Timon McPhearson, Timon McPhearson   +14 more
doaj   +1 more source

Projective Connections and Projective Transformations [PDF]

Nagoya Mathematical Journal, 1957
The main purpose of the present paper is to establish a theorem concerning the relation between the group of all projective transformations on an affinely connected manifold and the group of all affine transformations.
openaire   +2 more sources

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

The Spread of Descriptive Geometry in Great Britain Between the XVIII and XIX Century

Diségno, 2018
Tra il XVIII e il XIX secolo la diffusione della Geometria descrittiva di Monge in Europa determina, con tempi ed esiti diversi nei vari paesi, un cambiamento radicale nel campo della rappresentazione.
Stefano Chiarenza
doaj   +1 more source

Status, Change, and Futures of Zooplankton in the Southern Ocean

Frontiers in Ecology and Evolution, 2022
In the Southern Ocean, several zooplankton taxonomic groups, euphausiids, copepods, salps and pteropods, are notable because of their biomass and abundance and their roles in maintaining food webs and ecosystem structure and function, including the ...
Nadine M. Johnston, Eugene J. Murphy, Angus Atkinson, Andrew J. Constable, Andrew J. Constable, Cédric Cotté, Martin Cox, Kendra L. Daly, Ryan Driscoll, Hauke Flores, Svenja Halfter, Natasha Henschke, Simeon L. Hill, Juan Höfer, Juan Höfer, Brian P. V. Hunt, Brian P. V. Hunt, Brian P. V. Hunt, So Kawaguchi, Dhugal Lindsay, Cecilia Liszka, Valerie Loeb, Clara Manno, Bettina Meyer, Bettina Meyer, Bettina Meyer, Evgeny A. Pakhomov, Evgeny A. Pakhomov, Evgeny A. Pakhomov, Matthew H. Pinkerton, Christian S. Reiss, Kate Richerson, Walker O. Smith Jr., Walker O. Smith Jr., Deborah K. Steinberg, Kerrie M. Swadling, Geraint A. Tarling, Sally E. Thorpe, Devi Veytia, Peter Ward, Christine K. Weldrick, Guang Yang   +41 more
doaj   +1 more source

Project games [PDF]

International Journal of Game Theory, 2005
This research paper is devoted to a direct approach based on cooperative game theory to analyze the allocation issues in delayed project situations, completed with the examination of the opposite setting where the activities may be expedited but not delayed and their combination.
Arantza Estévez-Fernández, Peter Borm, Herbert Hamers   +2 more
openaire   +8 more sources