Results 21 to 30 of about 354,550 (267)

Pharmacokinetic and Pharmacodynamic Effects of Oral CXA‐10, a Nitro Fatty Acid, After Single and Multiple Ascending Doses in Healthy and Obese Subjects

open access: yesClinical and Translational Science, 2019
10‐nitro‐9(E)‐octadec‐9‐enoic acid (CXA‐10), a novel nitro fatty acid compound, demonstrates potential as a therapeutic agent in multiple disease indications in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play ...
Rachel M. Garner   +3 more
doaj   +1 more source

Projected changes in mean climate and extremes from downscaled high-resolution CMIP6 simulations in Australia

open access: yesWeather and Climate Extremes
High-resolution climate change projections are required to evaluate local and regional climate change impacts. We used CCAM (Conformal Cubic Atmospheric Model) to dynamically downscale CMIP6 GCMs (Global Climate Models) over Australia under three ...
Sarah Chapman   +4 more
doaj   +1 more source

Optogenetic stimulation of Kiss1ARC terminals in the AVPV induces surge-like luteinizing hormone secretion via glutamate release in mice

open access: yesFrontiers in Endocrinology, 2022
Kisspeptin neurons are mainly located in the arcuate (Kiss1ARC, vis-à-vis the GnRH pulse generator) and anteroventral periventricular nucleus (Kiss1AVPV, vis-à-vis the GnRH surge generator).
Xi Shen   +8 more
doaj   +1 more source

Evaluating Knowledge Gaps in Sea‐Level Rise Assessments From the United States

open access: yesEarth's Future, 2023
There have been many scientific advances regarding future sea‐level projections, however it is unclear if these have been transferred to assessment reports used by stakeholders.
Andra J. Garner   +5 more
doaj   +1 more source

Frameworks to envision equitable urban futures in a changing climate: A multi-level, multidisciplinary case study of New York City

open access: yesFrontiers in Built Environment, 2022
Cities are at the forefront of climate change action and planning for futures that are concomitantly more resilient and equitable, making local goals imperative for global sustainability. Under the multiple challenges of changing climatic, ecological and
Deborah Balk   +14 more
doaj   +1 more source

Projection in Interaction and Projection in Grammar [PDF]

open access: yesText - Interdisciplinary Journal for the Study of Discourse, 2005
AbstractIn this paper, I argue that there are fundamental common features shared by interaction and grammar that suggest some kind of interdependence between the two and a nonautonomy of the language faculty; one of these fundamental common features is that of ‘projectability’.
openaire   +3 more sources

The Spread of Descriptive Geometry in Great Britain Between the XVIII and XIX Century

open access: yesDiségno, 2018
Tra il XVIII e il XIX secolo la diffusione della Geometria descrittiva di Monge in Europa determina, con tempi ed esiti diversi nei vari paesi, un cambiamento radicale nel campo della rappresentazione.
Stefano Chiarenza
doaj   +1 more source

Status, Change, and Futures of Zooplankton in the Southern Ocean

open access: yesFrontiers in Ecology and Evolution, 2022
In the Southern Ocean, several zooplankton taxonomic groups, euphausiids, copepods, salps and pteropods, are notable because of their biomass and abundance and their roles in maintaining food webs and ecosystem structure and function, including the ...
Nadine M. Johnston   +41 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier   +10 more
wiley   +1 more source

Uncertainty, populism and foreign direct investment: the state of play in economic research

open access: yesPublic Sector Economics
This paper provides a synthesized, critical overview of the latest economic literature regarding the linkage between three concepts – uncertainty, populism and foreign direct investment.
Marijana Andrijić
doaj   +1 more source

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