Results 41 to 50 of about 353,264 (267)
npj Natural HazardsWe investigated projected changes to daily mean, common extreme (99th and 99.7th percentile), and rare extreme (annual exceedance probability (AEP) 1 in 10, 50, and 100) precipitation events across Australia and its greater capital cities using a large ...
Rohan Eccles +8 more
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Political Theory, 2001 This is a preprint (author's original) version of the article published in Political Theory 29(1):86-90. The final version of the article can be found at http://www.jstor.org/stable/3072545 (login required to access content). The version made available in Digital Common was supplied by the author.
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Journal of Cheminformatics, 2019 Abstract The chemfp project has had four main goals: (1) promote the FPS format as a text-based exchange format for dense binary cheminformatics fingerprints, (2) develop a high-performance implementation of the BitBound algorithm that could be used as an effective baseline to benchmark new similarity search implementations, (3 ...
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The global burden of smoking-related prostate cancer from 1990 to 2021 and projections to 2031
Tobacco Induced DiseasesIntroduction Smoking is a significant risk factor for prostate cancer (PCa), a major health threat for aging males globally. This study evaluates the worldwide burden of smoking-related PCa from 1990 to 2021 and projects trends to 2031.
Qian Cai‡ +8 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Selective Database Projections Based Approach for Mining High-Utility Itemsets
IEEE Access, 2018 High-utility itemset mining (HilIM) is an emerging area of data mining and is widely used. HilIM differs from the frequent itemset mining (FIM), as the latter considers only the frequency factor, whereas the former has been designed to address both ...
Anita Bai +2 more
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AGU Advances, 2023 Combining new constraints on future socio‐economic trajectories and the climate system's response to emissions can substantially reduce the projection uncertainty currently clouding regional climate adaptation decisions—more than either constraint ...
Flavio Lehner +4 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source