Results 51 to 60 of about 353,264 (267)
The calculation of simple ages in population projections [PDF]
Población y Desarrollo, 2018 This study describes a method of interpolation to disaggregate into single ages populations estimated or projected by five-year age groups. The method - minimum roughness - obviates the problem of spurious variations, which is a rather frequent problem ...
Ricardo F. Neupert
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
AxiomsThis study introduces two novel methodologies for solving systems of Fredholm integral equations, with particular emphasis on second-kind equations. The first method integrates the Sinc-collocation technique with a newly developed singular exponential ...
Saeed Althubiti, Abdelaziz Mennouni
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From organising as projects to projects as organisations
International Journal of Project Management, 2008 Nowadays, projects and project management can be found in virtually all organisations. Accordingly, preventing project failure has become increasingly critical. In light of this, attempts have been made to redefine the conceptual bases of project management and to define new avenues for research, development of the field, and practical application.
Molloy, E, van Donk, D
openaire +3 more sources
Prediction in projection [PDF]
Chaos: An Interdisciplinary Journal of Nonlinear Science, 2015 Prediction models that capture and use the structure of state-space dynamics can be very effective. In practice, however, one rarely has access to full information about that structure, and accurate reconstruction of the dynamics from scalar time-series data—e.g., via delay-coordinate embedding—can be a real challenge.
Joshua Garland, Elizabeth Bradley
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Projections of Antichains [PDF]
The Electronic Journal of Combinatorics, 2020 A subset $A$ of $\mathbb{Z}^n$ is called a weak antichain if it does not contain two elements $x$ and $y$ satisfying $x_i<y_i$ for all $i$. Engel, Mitsis, Pelekis and Reiher showed that for any weak antichain $A$, the sum of the sizes of its $(n-1)$-dimensional projections must be at least as large as its size $|A|$.
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Frontiers in AgingBackgroundThis study aims to analyze the historical trends of inflammatory bowel disease (IBD) burden in the elderly from 1990 to 2021 and forecast future trends up to 2051.MethodsData from the Global Burden of Disease Study 2021 were utilized.
Ying Liu +5 more
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