Results 61 to 70 of about 353,264 (267)

The Life Project [PDF]

Electronic Workshops in Computing, 2012
The Life Project explores issues of psychological projection into technology by diving into the convoluted relationship between practical purpose and emotional attachment, through both the creative act of designing and making robot entities with artificial emotions, and the social act of engaging with them.
Baker, C, French, F, Raskob, E, Rothwell, N   +3 more
openaire   +4 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The MAJORANA Project

Journal of Physics: Conference Series, 2009
Building a \BBz experiment with the ability to probe neutrino mass in the inverted hierarchy region requires the combination of a large detector mass sensitive to \BBz, on the order of 1-tonne, and unprecedented background levels, on the order of or less than 1 count per year in the \BBz signal region. The MAJORANA Collaboration proposes a design based
Varner, R.L., Schubert, A.G., Bertrand, F.E., Shirchenko, M., Farmer, T., Johnson, R.A., Myers, A.W., Yin, Z.-B., Hossbach, T., Finnerty, P., Ejiri, H., Akashi-Ronquest, M., Howe, M.A., Marino, M.G., Efremenko, Yu., Boswell, M., Vetter, K., Doe, P.J., Guiseppe, V.E., Wouters, J.M., Miley, H.S., Fast, J., Nomachi, M., Elliott, S.R., Hoppe, E., Chan, Y.-D., Amsbaugh, J.F., Greenberg, C., Dunmore, J.A., Kidd, M., Burritt, T.H., Tornow, W., Barbeau, P., Wilkerson, J.F., Timkin, V., Kephart, J., Hallin, L., Amman, M., Orrell, J., Shima, T., Fujikawa, B., Hurley, D., Bugg, W., Egorov, V., Keller, C., Odom, B., MacMullin, S., Gusey, K., Cianciolo, T.V., Hazama, R., Creswick, R., Luke, P., Barabash, A.S., Aalseth, C.E., Vanyushin, I., Yakushev, E., Leviner, L., Detwiler, J.A., Collar, J., Kouzes, R.T., Yu, C.-H., Kochetov, O., Rykaczewski, K.P., Tull, C., Robertson, R.G.H., Keillor, M., Back, H.O., Farach, H., McDonald, A.B., Young, A.R., Ely, J., Bergevin, M., Hime, A., Warner, R., Rodriguez, L., Thompson, R., Poon, A.W.P., Baktash, C., Cromaz, M., Konovalov, S.I., Radford, D.C., Van Wechel, T.D., Hyronimus, B., Mei, D.-M., Riley, N., Esterline, J., Rielage, K., Henning, R., Avignone, F.T., III, Beene, J.R., Gehman, V.M., Brudanin, V., Prior, G., Reeves, J.H., Yumatov, V., Lesko, K.T.   +95 more
openaire   +2 more sources

The Boltzmann project [PDF]

Metrologia, 2018
Abstract The International Committee for Weights and Measures (CIPM), at its meeting in October 2017, followed the recommendation of the Consultative Committee for Units (CCU) on the redefinition of the kilogram, ampere, kelvin and mole. For the redefinition of the kelvin, the Boltzmann constant will be fixed with
J. Fischer, B. Fellmuth, C. Gaiser, T. Zandt, L. Pitre, F. Sparasci, M. D. Plimmer, M. de Podesta, R. Underwood, G. Sutton, G. Machin, R. M. Gavioso, D. Madonna Ripa, P. P. M. Steur, J. Qu, X. J. Feng, J. Zhang, M. R. Moldover, S. P. Benz, D. R. White, L. Gianfrani, A. Castrillo, L. Moretti, B. Darquié, E. Moufarej, C. Daussy, S. Briaudeau, O. Kozlova, L. Risegari, J. J. Segovia, M. C. Martín, D. del Campo   +31 more
openaire   +6 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Projections of Lightning‐Ignited Wildfire Risk in the Western United States

Earth's Future
Cloud‐to‐ground (CG) lightning is a major source of summer wildfire ignition in the western United States (WUS). However, future projections of lightning are uncertain since lightning is not directly simulated by most global climate models.
Dmitri A. Kalashnikov, John T. Abatzoglou, Frances V. Davenport, Zachary M. Labe, Paul C. Loikith, Danielle Touma, Deepti Singh   +6 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

De l’art de re-présenter l’archéologie

Les Nouvelles de l’Archéologie, 2013
A conversation between contemporary art and archaeology seems to have been initiated. Far to be only an inspiration for contemporary art, archaeology could find, by this kind of interplays, a way to get perceptible some of its epistemological ...
Pierre-Antoine Le Nay
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source