Results 71 to 80 of about 1,461,323 (289)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Frontiers in AgingBackgroundThis study aims to analyze the historical trends of inflammatory bowel disease (IBD) burden in the elderly from 1990 to 2021 and forecast future trends up to 2051.MethodsData from the Global Burden of Disease Study 2021 were utilized.
Ying Liu +5 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Political Theory, 2001 This is a preprint (author's original) version of the article published in Political Theory 29(1):86-90. The final version of the article can be found at http://www.jstor.org/stable/3072545 (login required to access content). The version made available in Digital Common was supplied by the author.
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Projections of Lightning‐Ignited Wildfire Risk in the Western United States
Earth's FutureCloud‐to‐ground (CG) lightning is a major source of summer wildfire ignition in the western United States (WUS). However, future projections of lightning are uncertain since lightning is not directly simulated by most global climate models.
Dmitri A. Kalashnikov +6 more
doaj +1 more source
World population projections, 2020 [PDF]
The world's population, today numbering some 5.5 billion people, may approach 12 billion by the end of the next century. By the year 2020, 26 years from today, it will most likely have increased by about 2.5 billion to a total of 8 billion people, an ...
Nygaard, David F.
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
De l’art de re-présenter l’archéologie
Les Nouvelles de l’Archéologie, 2013 A conversation between contemporary art and archaeology seems to have been initiated. Far to be only an inspiration for contemporary art, archaeology could find, by this kind of interplays, a way to get perceptible some of its epistemological ...
Pierre-Antoine Le Nay
doaj +1 more source