Results 101 to 110 of about 1,329,018 (301)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
, 1999 This thesis is concerned with Hopf hypersurfaces of Kähler and nearly Kähler manifolds and gives special emphasis to the cases of hypersurfaces of complex projective spaces and of the 6-sphere endowed with its nearly Kähler almost complex structure ...
Martins, J.K., Martins, José Kenedy
core
On a generalization of I-regularity
Open MathematicsLet SS be a pomonoid. The projectivity and strong flatness of right SS-posets have been central topics in the homological classification of pomonoids in recent decades. In 2005, Shi et al. introduced II-regular SS-posets and proved that all its cyclic SS-
Qiao Husheng, Feng Leting
doaj +1 more source
Starter Projects in Python Programming Classes
, 2022 Starter projects are part of constructionist learning arrangements (1, 2). The term was mainly coined by the Scratch community and describes a simple, executable program that is designed to encourage copying, exploring and further development. This contribution first discusses three types: test programs, examples that illustrate programming techniques ...
openaire +2 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Naive motivic homotopy classes of endomorphisms of the projective line [PDF]
, 2020 Vi studerer naive motiviske homotopiklasser av endomorfier av den projektive linja over en kropp. Først redegjør vi for Cazanaves resultat om at den kanoniske funksjonen fra naive til motiviske homotopiklasser er en gruppekomplettering. Så fortsetter med
Balch Barth, Viktor
core
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
MathematicsRecently, Gorenstein dimensions relative to a semidualizing module have been the subject of numerous studies with interesting extensions of the classical homological dimensions.
Enrique Duarte +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Quaternionic Line Bundles over Quaternionic Projective Spaces [PDF]
, 2006 Spreafico, Mauro +1 more
core +1 more source