Results 81 to 90 of about 1,329,018 (301)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Infinitely many securities and the fundamental theorem of asset pricing [PDF]
, 2004 Several authors have pointed out the possible absence of martingale measures for static arbitrage-free markets with an infinite number of available securities.
Balbás, Alejandro, Downarowicz, Anna
core +1 more source
The Journal of Political Theory, Political Philosophy and Sociology of Politics Politeia, 2020 The concept “multitude”, popular in political philosophy, largely owes its entrance into the modern political vocabulary to the efforts of Antonio Negri, the Italian philosopher. His research from the 1980s and 1990s gave rise to a synthetic philosophical theory that views multitude as a key element in the political struggle of the left, thereby giving
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Imersões de variedades em espaços euclideanos [PDF]
, 1982 Dissertaçao (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Curso de Pós-Graduação em Matemática, Florianópolis ...
D'alascio, Maria José
core
The Fisher-Rao metric for projective transformations of the line [PDF]
, 2005 A conditional probability density function is defined for measurements arising from a projective transformation of the line. The conditional density is a member of a parameterised family of densities in which the parameter takes values in the three ...
Stephen J. Maybank, Maybank, Stephen J.
core +1 more source
Locally adequate semigroup algebras
Open Mathematics, 2016 We build up a multiplicative basis for a locally adequate concordant semigroup algebra by constructing Rukolaĭne idempotents. This allows us to decompose the locally adequate concordant semigroup algebra into a direct product of primitive abundant 0-J*$0{
Ji Yingdan, Luo Yanfeng
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source