Results 71 to 80 of about 190,046 (323)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Relativistic Localizing Processes Bespeak an Inevitable Projective Geometry of Spacetime
Advances in High Energy Physics, 2017 Surprisingly, the issue of events localization in spacetime is poorly understood and a fortiori realized even in the context of Einstein’s relativity.
Jacques L. Rubin
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Line Spreads That Produce Projective Planes
MathematicsWe explicitly classify those line spreads of projective 5-space over a field that have the property that the given spread induces a spread in the 3-space generated by any pair of spread lines.
Hendrik Van Maldeghem
doaj +1 more source
Interpretation of Geometry on Manifolds as a Geometry in a Space with Projective Metric [PDF]
, 2022 A. Artikbaev, S. S. Saitova
openalex +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Roots of maps between spheres and projective spaces in codimension one [PDF]
, 2020 Marcio Colombo Fenille +2 more
openalex +1 more source
Differentiating the State Evaluation Map from Matrices to Functions on Projective Space [PDF]
, 2023 Ghaliah Alhamzi, Edwin Beggs
openalex +1 more source