Results 71 to 80 of about 188,835 (324)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Neural Network-Based Projective Grid Model for Learning Representation of Surface and Wave Foams

open access: yesIEEE Access
In this paper, we propose a projective grid model that enables learning representation of foam effects using artificial neural networks. In 3D fluid simulations, foam is one of the most representative secondary effects in water.
Jong-Hyun Kim
doaj   +1 more source

The block structure spaces of real projective spaces and orthogonal calculus of functors

open access: yes, 2006
Given a compact manifold X, the set of simple manifold structures on X x \Delta^k relative to the boundary can be viewed as the k-th homotopy group of a space \S^s (X). This space is called the block structure space of X.
Macko, Tibor
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Universal Entire Curves in Projective Spaces with Slow Growth [PDF]

open access: green, 2023
Zhangchi Chen   +2 more
openalex   +1 more source

On projections of metric spaces

open access: yesJournal of Computational Geometry, 2011
Journal of Computational Geometry, Vol. 5 No. 1 (2014)
openaire   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Line Spreads That Produce Projective Planes

open access: yesMathematics
We explicitly classify those line spreads of projective 5-space over a field that have the property that the given spread induces a spread in the 3-space generated by any pair of spread lines.
Hendrik Van Maldeghem
doaj   +1 more source

Relativistic Localizing Processes Bespeak an Inevitable Projective Geometry of Spacetime

open access: yesAdvances in High Energy Physics, 2017
Surprisingly, the issue of events localization in spacetime is poorly understood and a fortiori realized even in the context of Einstein’s relativity.
Jacques L. Rubin
doaj   +1 more source

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