Results 71 to 80 of about 103,657 (309)

Adequação ao Real de adolescentes: possibilidades informativas do Questionário Desiderativo

Psicologia: Teoria e Pesquisa
O presente trabalho constitui-se em um recorte de uma investigação voltada para a busca de padrões de desempenho de adolescentes diante do Questionário Desiderativo. Responderam, individualmente, a essa técnica projetiva, 120 adolescentes, voluntários de
Nicole Medeiros Guimarães, Sonia Regina Pasian   +1 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Interpretation in Psychology and Social Science—New Approach or a Neglected Tradition?

Forum: Qualitative Social Research, 2003
The recent claims for an emergent interpretative paradigm in psychology and the social sciences is evaluated in the context of the long tradition of such methodologies in psychology.
Jochen Fahrenberg
doaj  

Linear Invariant Systems Theory for Signal Enhancement [PDF]

, 2011
This paper discusses a linear time invariant (LTI) systems approach to signal enhancement via projective subspace techniques. It provides closed form expressions for the frequency response of data adaptive finite impulse response eigenfilters.
Georgieva, P., Lang, Elmar W., Miguel, G., Teixeira, A. J. S., Teixeira, Ana Rita, Tomé, A.M.   +5 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Brazilian norms for the International Affective Picture System (IAPS): comparison of the affective ratings for new stimuli between Brazilian and North-American subjects Normas Brasileiras para o International Affective Picture System (IAPS): estudo comparativo dos novos estímulos para avaliações afetivas entre sujeitos brasileiros e norte-americanos

Jornal Brasileiro de Psiquiatria, 2008
OBJECTIVE: The study presents the Brazilian norms for 240 new stimuli from International Affective Picture System (IAPS), a database of affective images widely used in research, compared to the North-American normative ratings.
Cristina Lasaitis, Rafaela Larsen Ribeiro, Orlando Francisco Amodeo Bueno   +2 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Analyzing Music Services Positioning Through Qualitative Research

Tržište, 2015
Information technologies have produced new ways of distributing and consuming music, mainly by youth, in relation to both goods and services. In the case of goods, there has been a dramatic shift from traditional ways of buying and listening to music to ...
Manuel Cuadrado, María José Miquel, Juan D. Montoro   +2 more
doaj  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Projective techniques: Are they a victim of clashing paradigms? [PDF]

This paper reviews the concept and historical development of projective techniques. It considers why, given the importance of their psychoanalytical foundations to the underlying paradigms of management theory, they have been generally marginalised as a ...
Boddy, Clive R., Bond, Derek, Ramsey, Elaine   +2 more
core   +1 more source