Results 21 to 30 of about 68,533 (261)
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
Projekt statutu i regulaminu archiwum diecezjalnego
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Stanisław Librowski
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
U radu su prikazani projektovanje i realizacija fotonaponske elektrane izlazne snage 1500 kW na krovu hale fabrike „Flash“ u Apatinu. Solarna elektrana je povezana na NN sabirnice u transformatorskoj stanici 20/0.4 kV 1600 kVA i preko njih napaja ...
Marko Đurović +2 more
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Strategia poszukiwania pomysłów na projekt
Współczesny świat wykazuje coraz większy strumień zmian. Każda zmiana wprowadza do decyzji zarządczej nowy udział w niepewności, pojawieniu się.
Svitlana Ivanova +3 more
doaj +1 more source
Projekt jako metoda zarządzania – wyzwania i szanse dla administracji publicznej w Polsce
Celem artykułu jest przedstawienie wybranych rozwiązań zarządzania projektami w administracji publicznej, które nie wynikały z konieczności realizacji zadań związanych z zarządzaniem funduszami UE lub realizacji projektów współfinansowanych z tych ...
Jacek Cheda, Bartosz Rzętkiewicz
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Umweltverträglichkeitsuntersuchungen in der Praxis anhand zweier Beispiele
Beide Beispiele zeigen deutlich auf welche Stellung Umweltverträglichkeitsuntersuchungen in der Regionalplanung oder im Raumordnungsverfahren haben bzw. noch verstärkt haben könnten. Die Regionalplanung für das Raumordnungsverfahren dient u. a. auch zur
Reinhard Schultz
doaj +1 more source

