Results 161 to 170 of about 4,979 (192)
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Erythromycin as a gastrointestinal prokinetic agent
Intensive and Critical Care Nursing, 2001Erythromycin is a potent stimulator of gastrointestinal (GI) motility and can be a useful agent to treat GI stasis in patients who are critically ill. However, it is not licensed for this indication and has serious drug interactions which may limit its utility.
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PROKINETIC AGENTS IN POSTGASTRECTOMY PATIENTS
Gastroenterology Clinics of North America, 1994Postgastrectomy syndromes are uncommon but, unfortunately, frustrating for both patient and physician, because treatment with prokinetic agents is often of limited benefit. This article examines the evidence for efficacy of available prokinetic drugs in the management of these difficult disorders.
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Is Rectally Administered Cisapride an Effective Prokinetic Agent?
Annals of Pharmacotherapy, 1999OBJECTIVE: To summarize the published data on the efficacy of rectally administered cisapride. DATA SOURCES: Published double-blind, placebo-controlled trials on rectally administered cisapride identified by MEDLINE (January 1966 ...
M A, Gales, D W, Harms
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Erythromycin stearate as prokinetic agent in postvagotomy gastroparesis
Digestive Diseases and Sciences, 1990We describe a patient with severe postvagotomy gastroparesis who failed standard medical therapy but had an excellent clinical and radiological response to 250 mg of erythromycin administered 30 min before each meal. Improvement was further documented by a marked improvement in this patient's 99m Tc-sulfur colloid radionuclide gastric emptying ...
H, Mozwecz +5 more
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Prokinetic agents for lower gastrointestinal motility disorders
Diseases of the Colon & Rectum, 1993Prokinetic agents are currently being investigated as potential therapies for motility disorders of the lower gastrointestinal tract. Cholinergic agonists such as bethanechol are known to improve postoperative ileus but are limited because of side effects. Dopamine antagonists such as domperidone appear to have maximal prokinetic effect in the proximal
W E, Longo, A M, Vernava
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Use of prokinetic agents in special populations
American Journal of Health-System Pharmacy, 1996The use of prokinetic agents by pediatric patients, geriatric patients, and patients taking other drugs that may affect or be affected by the prokinetic agent is reviewed. The use of such agents to treat motility disorders has expanded over the past few years.
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Can naloxone be a prokinetic agent in sepsis?
Clinical Intensive Care, 2001Objective: The aim of this study was to investigate whether the use of Naloxone (Nx) may prove effective as a prokinetic agent in a septic model in rats. Design: 100 male Swiss-Albino rats were divided in five groups. All rats were housed under standard environmental conditions and fasted for 18 hours.
M Sakaryaa +5 more
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The effects of renzapride, a novel prokinetic agent, in diabetic gastroparesis
Alimentary Pharmacology & Therapeutics, 1991SUMMARYGastric emptying was measured in 9 diabetic patients with autonomic neuropathy (Group 1) and 8 normal controls (Group 2) on 4 occasions after swallowing placebo, 0.5, 1.0 or 2.0 mg of the newly developed prokinetic drug renzapride given doubleāblind and in random order.
A D, Mackie +5 more
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Efficacy of Prokinetic Agents in Improving Bowel Preparation for Colonoscopy
Digestion, 2008<i>Background and Aim: </i>Colonoscopy plays an important role in the diagnosis and treatment of gastrointestinal illness in both Western countries and Japan. However, preparative bowel cleansing for colonoscopy is frequently troublesome for elderly and/or constipated patients, since they must drink larger volumes of lavage solution for ...
Yuko, Mishima +9 more
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Recent developments in gastrointestinal prokinetic agents
Expert Opinion on Therapeutic Patents, 2008Background: Prokinetic agents are employed to reverse impaired gastrointestinal motility arising from functional disorders such as constipation-dependent irritable bowel syndrome and functional dyspepsia, as well as chronic constipation and gastro-oesophageal reflux disease.
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