Results 61 to 70 of about 4,973 (169)

Lubiprostone Improves Distal Segment-Specific Colonic Contractions through TRPC4 Activation Stimulated by EP3 Prostanoid Receptor

Pharmaceuticals
Background: Prokinetic agents are effective in increasing gastrointestinal (GI) contractility and alleviating constipation, often caused by slow intestinal motility. Lubiprostone (LUB), known for activating CLC-2 chloride channels, increases the chloride
Byeongseok Jeong, Jun Hyung Lee, Jin-A Lee, Seong Jung Kim, Junhyung Lee, Insuk So, Jae Yeoul Jun, Chansik Hong   +7 more
doaj   +1 more source

Superior Mesenteric Artery Syndrome in an 11-Year-Old Boy: A Case Report

Clinical Medicine Insights: Case Reports
Superior Mesenteric Artery Syndrome (SMAS) is a rare but potentially life-threatening condition caused by the compression of the duodenum by the superior mesenteric artery.
Sakar Babu Gharti, Nischal Shrestha, Kaushal Samsher Thapa, Rajat Shah, Priti Khanal, Rajnish Kumar Shah, Sanjeeb Babu Gharti, Umesh Tiwari   +7 more
doaj   +1 more source

Prucalopride: safety, efficacy and potential applications

Therapeutic Advances in Gastroenterology, 2012
Chronic constipation is a very common functional gastrointestinal disorder which can be associated with significant impairments in quality of life for some people with the condition.
Eamonn M. M. Quigley
doaj   +1 more source

Use of prokinetic agents in hospitalised adult patients: Protocol for a scoping review. [PDF]

Acta Anaesthesiol Scand, 2022
Crone V, Møller MH, Perner A, Alhazzani W, Krag M.   +4 more
europepmc   +1 more source

Contraction of gut smooth muscle cells assessed by fluorescence imaging

Journal of Pharmacological Sciences, 2015
Here we discuss the development of a novel cell imaging system for the evaluation of smooth muscle cell (SMC) contraction. SMCs were isolated from the circular and longitudinal muscular layers of mouse small intestine by enzymatic digestion.
Yohei Tokita, Hirotada Akiho, Kazuhiko Nakamura, Eikichi Ihara, Masahiro Yamamoto   +4 more
doaj   +1 more source

Do prokinetic agents provide symptom relief through acceleration of gastric emptying? An update and revision of the existing evidence. [PDF]

United European Gastroenterol J, 2023
Goelen N, Jones M, Huang IH, Carbone F, Janssen P, Tack J.   +5 more
europepmc   +1 more source

Effects of prokinetic drugs on the abdominal wall wound healing of rats submitted to segmental colectomy and colonic anastomosis Efeitos de drogas procinéticas na cicatrização da parede abdominal de ratos submetidos à colectomia segmentar e anastomose no cólon esquerdo

Acta Cirúrgica Brasileira, 2012
PURPOSE: To assess the effect of prokinetic agents on abdominal wall wound healing in rats submitted to segmental colectomy and colonic anastomosis. METHODS: Sixty rats were randomly allocated into three groups according to the agents they would receive ...
Pedro Henrique Alves de Morais, Naiara Galvão da Silva, Marcos Vinícius Melo de Oliveira, Alexandre Malta Brandão, Silvana Marques e Silva, Fabiana Pirani Carneiro, João Batista de Sousa   +6 more
doaj   +1 more source

Analysis of the Efficacy of Tiaozhong Yiqi Soup on Elderly Qi Deficiency Type Slow Transit Constipation [PDF]

Zhongguo quanke yixue
Background Tiaozhong Yiqi Soup was first used to treat gastrointestinal diseases caused by spleen deficiency and dampness stagnation. Years of experience in treating slow transit constipation (STC) in the elderly through the addition or subtraction of ...
ZHAO Hongbo, WU Xiaojing, YANG Yun, GE Zhiming, FAN Xianxian, ZHAO Lan, WANG Hongwei
doaj   +1 more source

From diarrhoea to duodenal stricture: Contrast computed tomography and portal vein gas enhance disease staging

Equine Veterinary Education, Volume 38, Issue 10, Page 516-518, October 2026.
C. A. McKinney‐Aguirre, N. S. Browne
wiley   +1 more source

Effect of Sihogyeji-tang on functional dyspepsia: a systematic review and meta-analysis

Frontiers in Pharmacology
IntroductionFunctional dyspepsia (FD) has a global prevalence of approximately 15% and is characterized by chronic symptoms with an unclear etiology. Herbal medicines, owing to their multifaceted mechanisms, are promising therapeutic options for FD. This
Hanbum Bae, Jinsung Kim, Soyeon Kim, Soyeon Kim   +3 more
doaj   +1 more source