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Prolactin exists in man as a distinct and separate anterior pituitary hormone from growth hormone. It is important in lactation and the control of gonadal function, although it may have a much wider and basic metabolic role, similar to its role in lower forms. In clinical endocrinology it is important as an index of pituitary and hypothalamic diseases;
Hörl, R. +5 more
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ContextProlactin, a hormone synthesized by the anterior pituitary gland demonstrates promise as a neuroprotective agent, however, its role in humans and in vivo during injury is not fully understood.ObjectiveTo investigate whether elevated levels of ...
David A Paul +9 more
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Background: Stress-induced hyperprolactinemia can be difficult to differentiate from true hyperprolactinema and may result in patients having unnecessary investigations and imaging.
Raya Almazrouei +3 more
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Prolactin, a hormone secreted by the anterior pituitary, exists in three major forms in circulation. The macroprolactin form is biologically inactive but contributes to elevated serum prolactin concentrations.
Pallavi Chincholkar +2 more
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The brain as a source and a target of prolactin in mammals
Prolactin is a polypeptide hormone associated with an extensive variety of biological functions. Among the roles of prolactin in vertebrates, some were preserved throughout evolution.
Ana R Costa-Brito +2 more
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Circulating prolactin aberrations (chronically high or low concentrations) have been shown to have strong associations with ovarian dysfunction in African female elephants.
Natalia A. Prado +4 more
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Secretion and Function of Pituitary Prolactin in Evolutionary Perspective
The hypothalamo-pituitary system developed in early vertebrates. Prolactin is an ancient vertebrate hormone released from the pituitary that exerts particularly diverse functions.
Arpád Dobolyi +8 more
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Prolactin and vitiligo: proposed autocrine/paracrine actions
Background The exact cause of vitiligo remains unclear. Several theories have been proposed, including autoimmune and neuroendocrine theories. Prolactin has been studied as an immunomodulatory factor in several autoimmune diseases.
Ghada M El-Hanafy +3 more
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Anti-prolactin has a specific activity against prolactin. It neutralizes prolactin action in circulation. The effect of such neutralization is the inhibition of feather fall off process, so that hens may be able to produce eggs again. Anti-prolactin can
Erma Safitri
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Prolactin and Autoimmunity [PDF]
The great asymmetry of autoimmune diseases between genders represents one of the most enigmatic observations among the mosaic of autoimmunity. Sex hormones are believed to play a crucial role on this dimorphism. The higher prevalence of autoimmunity among women at childbearing ages, disease onset/relapses during pregnancy, and post-partum are some of ...
Vânia Vieira Borba +5 more
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