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Secretion and Function of Pituitary Prolactin in Evolutionary Perspective
The hypothalamo-pituitary system developed in early vertebrates. Prolactin is an ancient vertebrate hormone released from the pituitary that exerts particularly diverse functions.
Arpád Dobolyi +8 more
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Prolactin and vitiligo: proposed autocrine/paracrine actions
Background The exact cause of vitiligo remains unclear. Several theories have been proposed, including autoimmune and neuroendocrine theories. Prolactin has been studied as an immunomodulatory factor in several autoimmune diseases.
Ghada M El-Hanafy +3 more
doaj +1 more source
Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation [PDF]
Introduction The prolactin-Janus-kinase-2-signal transducer and activator of transcription-5 (JAK2-STAT5) pathway is essential for the development and functional differentiation of the mammary gland.
Liu, R. +26 more
core +2 more sources
Summary: Altered physiological states require neuronal adaptation. In late pregnancy and lactation, a sub-population of the mouse hypothalamic tuberoinfundibular dopaminergic (TIDA) neurons alters their behavior to synthesize and release met-enkephalin ...
Siew H. Yip +9 more
doaj +1 more source
Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects [PDF]
Reboxetine is a selective noradrenaline reuptake inhibitor, whereas mirtazapine acts as an antagonist at noradrenergic alpha(2), serotonin (5-HT2), 5-HT3 and histamine H-1 receptors.
Baghai, Thomas C. +2 more
core +1 more source
Background Prolactin mirrors the dopaminergic activity in the brain which is key to understanding alcohol use disorders (AUD). Still, patients with AUD are a heterogenous group and there seem to be gender differences in the relationship between alcohol ...
Susmita Pandey +3 more
doaj +1 more source
Dynamic analysis of stochastic transcription cycles [PDF]
In individual mammalian cells the expression of some genes such as prolactin is highly variable over time and has been suggested to occur in stochastic pulses.
Davis, Julian R. E. +52 more
core +1 more source
The significance of prolactin in systemic connective tissue diseases
Objectives Does prolactin (PRL) level testing in the diagnosis of systemic connective tissue diseases make sense and should we test it in everyday practice?
Michał Piotr Jakubaszek
core +1 more source
Trauma of the head causes important changes in serum prolactin levels. Usually somatostatin has an inhibitory effect on the hormones. We do not know much about the effect of somatostatin on prolactin secretion.
Mithat Bahçeci +2 more
doaj +2 more sources
Effect of prolactin on casein synthesis of bovine mammary epithelial cells
The experiment studied the effect of prolactin on milk protein synthesis of bovine mammary epithelial cells (BMECs). The healthy breast tissue of Holstein cows was selected as the experimental material, BMECs were isolated, cultured and purified, and the
Ya-ya JIN +5 more
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