Results 61 to 70 of about 220,665 (364)
A 20-year prospective study of plasma prolactin as a risk marker of breast cancer development.
Understanding how the timing of exposure to endogenous hormones influences cancer development is critical to elucidating disease etiology. Prolactin increases proliferation and cell motility, processes important in later stage tumor development ...
S. Tworoger+6 more
semanticscholar +1 more source
Objective: Effects of conventional and atypical antipsychotics on bone mineral density (BMD) and serum prolactin levels (PRL) were examined in patients with schizophrenia.Methods: One hundred and sixty-three first-episode inpatients with schizophrenia ...
Cao, Bingyu+6 more
core +1 more source
TRH: Pathophysiologic and clinical implications [PDF]
Thyrotropin releasing hormone is thought to be a tonic stimulator of the pituitary TSH secretion regulating the setpoint of the thyrotrophs to the suppressive effect of thyroid hormones. The peptide stimulates the release of normal and elevated prolactin.
A. Enjalbert+82 more
core +1 more source
ABSTRACT The use of opioids is frequently associated with the occurrence of adverse effects during cesarean delivery, especially for primiparous women with severe preeclampsia, creating a critical need for investigation of alternative analgesic strategies.
Yong Yang, Ya‐Ni Zhang
wiley +1 more source
Circulating Prolactin Associates With Diabetes and Impaired Glucose Regulation
OBJECTIVE Prolactin is a major stimulus for the β-cell adaptation during gestation and guards postpartum women against gestational diabetes. Most studies of the role of prolactin on glucose metabolism have been conducted in humans and animals during ...
Tiange Wang+11 more
semanticscholar +1 more source
Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland [PDF]
We have demonstrated that insulin-like growth factor binding protein-5 (IGFBP-5) production by mammary epithelial cells increases dramatically during forced involution of the mammary gland in rats, mice and pigs.
Accorsi+60 more
core +1 more source
Abstract Background The treatment of levodopa‐induced dyskinesia in Parkinson's disease (PD) is a largely unmet need. Objectives Mesdopetam is a novel small molecule dopamine D3 receptor antagonist aimed for the treatment of levodopa‐induced dyskinesia.
Angelo Antonini+6 more
wiley +1 more source
Summary: Altered physiological states require neuronal adaptation. In late pregnancy and lactation, a sub-population of the mouse hypothalamic tuberoinfundibular dopaminergic (TIDA) neurons alters their behavior to synthesize and release met-enkephalin ...
Siew H. Yip+9 more
doaj
Stiff Collagen Matrices Increase Tumorigenic Prolactin Signaling in Breast Cancer Cells*
Background: Prolactin, but not its best studied mediator STAT5a, is associated with breast cancer progression. Results: In stiff but not compliant collagen matrices, prolactin promotes tumorigenic processes via an enhanced ERK1/2 cascade.
Craig E. Barcus+3 more
semanticscholar +1 more source