Results 71 to 80 of about 220,665 (364)

Activities of bone morphogenetic proteins in prolactin regulation by somatostatin analogs in rat pituitary GH3 cells [PDF]

, 2011
Involvement of the pituitary BMP system in the modulation of prolactin (PRL) secretion regulated by somatostatin analogs, including octreotide (OCT) and pasireotide (SOM230), and a dopamine agonist, bromocriptine (BRC), was examined in GH3 cells.
Inagaki, Kenichi, Iwasaki, Yasumasa, Makino, Hirofumi, Miyoshi, Tomoko, Nakamura, Eri, Ogura, Toshio, Otsuka, Fumio, Suzuki, Jiro, Tsukamoto, Naoko   +8 more
core   +1 more source

Safety and Effect of 12‐Month Ecopipam Treatment in Pediatric Patients with Tourette Syndrome

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Tourette syndrome (TS) is a chronic neurodevelopmental tic disorder with a considerable quality of life (QOL) burden. Objectives The goal was to determine the long‐term safety, tolerability, and clinical effects of ecopipam, a first‐in‐class dopamine D1 receptor antagonist, for TS.
Donald L. Gilbert, David J.B. Kim, Meredith M. Miller, Sarah D. Atkinson, George B. Karkanias, Frederick E. Munschauer, Stephen P. Wanaski, Timothy M. Cunniff   +7 more
wiley   +1 more source

Determination of Prolactin in Canine Saliva: Is It Possible to Use a Commercial ELISA Kit?

Animals, 2019
Prolactin has been reported to be a remarkable index of stress response, both acute and chronic, in several species. The use of biological matrixes other than blood is receiving increasing interest in the study of hormones, due to the lower invasiveness ...
Jara Gutiérrez, Angelo Gazzano, Beatrice Torracca, Valentina Meucci, Chiara Mariti   +4 more
doaj   +1 more source

Mutant prolactin receptor and familial hyperprolactinemia.

New England Journal of Medicine, 2013
Hyperprolactinemia that is not associated with gestation or the puerperium is usually due to tumors in the anterior pituitary gland and occurs occasionally in hereditary multiple endocrine neoplasia syndromes. Here, we report data from three sisters with
P. Newey, C. Gorvin, Stephen J Cleland, C. Willberg, M. Bridge, M. Azharuddin, Russell S Drummond, P. A. van der Merwe, P. Klenerman, C. Bountra, Rajesh V. Thakker   +10 more
semanticscholar   +1 more source

Evidence of Involvement of the Calcitonin Gene‐Related Peptide in Restless Legs Syndrome

Movement Disorders, EarlyView.
Abstract Background Restless legs syndrome (RLS) is a common sensory‐motor disorder characterized by an urge to move the legs, often with unpleasant sensations, particularly during rest. Current treatments include iron supplementation, dopamine agonists, and opioids, but new therapeutic approaches are needed.
Maria P. Mogavero, Mojibola Fowowe, Akeem Sanni, Mona Goli, Giuseppe Lanza, Francesca L'Episcopo, Luigi Ferini‐Strambi, Yehia Mechref, Raffaele Ferri   +8 more
wiley   +1 more source

Prolactin enzyme-linked immunosorbent assay for rhinoceroses – Another tool for assessing reproductive function and dysfunction in this taxon

Theriogenology Wild, 2023
For decades, progesterone and its metabolites have served as the primary biomarkers for monitoring reproductive activity in rhinoceroses, whereas protein hormones have received little attention despite their potential value in understanding reproductive ...
Terri L. Roth, Elizabeth M. Donelan, Louisa A. Rispoli, T. Reilly   +3 more
doaj  

Prolactin and cancer: Has the orphan finally found a home?

Indian Journal of Endocrinology and Metabolism, 2012
Prolactin has, for long, been associated with galactorrhea and infertility in women while its role in men is largely unknown. Recently, expression of prolactin in various other tissues like the breast, prostate, decidua, and the brain has been recognized.
Bipin Kumar Sethi, G V Chanukya, V Sri Nagesh   +2 more
doaj   +1 more source

The Hsp90β Isoform: An Attractive Target for Drug Development

Medicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury, Terin D'Amico, Brian S. J. Blagg   +2 more
wiley   +1 more source

Proteomic Profiling Informs Mechanisms of Esophageal Adenocarcinoma Inhibition by Cranberry Proanthocyanidins

Molecular Nutrition &Food Research, EarlyView.
In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang, Michelle Lee, Erika de Jesus, Katherine Weh, Connor Howard, Henriette Remmer, Amy B. Howell, Laura A. Kresty   +7 more
wiley   +1 more source

Prolactin and risk of preeclampsia: A single institution, cross-sectional study

Asian Pacific Journal of Reproduction, 2019
Objective: To illustrate the association between prolactin serum level and severity of preeclampsia. Methods: In this cross-sectional study, 31 pregnant women with preeclampsia were enrolled as Group I and 20 healthy pregnant women as Group II.
Thabat J Al-Maiahy, Ali I Al-Gareeb, Hayder M Al-kuraishy   +2 more
doaj   +1 more source