Results 11 to 20 of about 10,221 (208)

The pituitary TGFb1 system as a novel target for the treatment of resistant prolactinomas [PDF]

open access: yes, 2016
Prolactinomas are the most frequently observed pituitary adenomas and most of themrespond well to conventional treatment with dopamine agonists (DAs).
Camilletti, María Andrea   +3 more
core   +2 more sources

Sex differences in the pituitary TGFβ1 system: the role of TGFβ1 in prolactinoma development [PDF]

open access: yes, 2019
Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in tumor size, behavior and incidence have been described. These differences have been associated with earlier diagnosis in woman, as well as with serum estradiol ...
Abeledo Machado, Alejandra Inés   +6 more
core   +1 more source

A macroprolactinoma becoming resistant to cabergoline and developing atypical pathology [PDF]

open access: yes, 2016
Pituitary adenomas are a common intracranial neoplasm, usually demonstrating a benign phenotype. They can be classified according to pathological, radiological or clinical behaviour as typical, atypical or carcinomas, invasive or noninvasive, and ...
Ansorge, Olaf   +6 more
core   +3 more sources

Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]

open access: yes, 2001
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Gloddek, Jutta   +7 more
core   +1 more source

Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]

open access: yes, 2016
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia   +4 more
core   +2 more sources

The side effects of dopamine receptor agonist drugs in Chinese prolactinoma patients: a cross sectional study

open access: yesBMC Endocrine Disorders, 2022
Background Recently, side effects from Dopamine Receptor Agonist Drugs (DAs) in treating pituitary prolactinoma have raised widespread concern. This study explores the incidence and influencing factors of DAs-related side effects in Chinese prolactinoma ...
Xiaoan Ke   +7 more
doaj   +1 more source

Cabergoline Treatment in Invasive Giant Prolactinoma

open access: yesClinical Medicine Insights: Case Reports, 2014
Patients with invasive giant prolactinoma suffer from a constellation of symptoms including headache, blurred vision, lethargy, and sexual dysfunction. Cabergoline, a potent dopamine agonist, is a known medication prescribed for the treatment of invasive
Sadeem Alsubaie, Mussa H. Almalki
doaj   +1 more source

Increased expression of aromatase cytochrome P450 enzyme is associated with prolactinoma invasiveness in post-menopausal women

open access: yesJournal of International Medical Research, 2019
Objectives To investigate the expression levels of aromatase cytochrome P450 enzyme (P450AROM) and related molecules—estrogen receptor-beta (ER-β), Ki-67, and p53—in prolactinoma tumor tissue from pre- and post-menopausal women, and to determine the ...
Yin-Xia Su   +9 more
doaj   +1 more source

Prolactinoma presenting as chronic anaemia with osteoporosis: a case report

open access: yesJournal of Medical Case Reports, 2010
Introduction Unexplained anaemia is a rare mode of presentation for prolactinoma. We describe a case of a man, with chronic anaemia ascribed to old age.
Hanley John P, MacLean Fergus R
doaj   +1 more source

A scoping review to understand the indications, effectiveness, and limitations of cabergoline in radiological and biochemical remission of prolactinomas

open access: yesIndian Journal of Endocrinology and Metabolism, 2021
Cabergoline has long been used in the medical management of prolactin-secreting pituitary adenomas. However, there is contradicting and inadequate evidence on the efficacy of cabergoline in achieving radiological and biochemical remission in prolactinoma.
Rakesh Mishra   +5 more
doaj   +1 more source

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