Results 11 to 20 of about 17,963 (297)

Treatment of Prolactinoma

open access: yesMedicina, 2022
Prolactinomas are the commonest form of pituitary neuroendocrine tumor (PitNET), representing approximately half of such tumors. Dopamine agonists (DAs) have traditionally been the primary treatment for the majority of prolactinomas, with surgery ...
W. Inder, C. Jang
semanticscholar   +4 more sources

Giant prolactinoma with progressive cranial settling and central herniation: a case report [PDF]

open access: yesJournal of Medical Case Reports
Background Giant prolactinoma (size > 4 cm) is a rare condition and accounts for less than 1% of pituitary adenomas. In even rarer cases, these lesions may involve craniocervical structures requiring surgical intervention. The present case is the largest
Taha Shahbazi   +3 more
doaj   +2 more sources

Transcriptomic analysis of the anti-tumor effects of leflunomide in prolactinoma [PDF]

open access: yesScientific Reports
Leflunomide’s anti-tumor effects have been investigated in various types of tumors; however, its impact on pituitary adenoma, particularly prolactinoma, is unclear.
Xiangdong Pei   +6 more
doaj   +2 more sources

Cholesterol-activated stress granules reduce the membrane localization of DRD2 and promote prolactinoma dopamine agonists resistance [PDF]

open access: yesActa Neuropathologica Communications
Prolactinoma is the most prevalent pituitary neuroendocrine tumor and dopamine agonists (DAs) targeting dopamine D2 receptor (DRD2) are recommended as the first-line treatment. However, varying degrees of DA resistance limit patient benefit.
Yuyang Peng   +8 more
doaj   +2 more sources

Advances in the treatment of prolactinomas [PDF]

open access: yesEndocrine Reviews, 2006
Prolactinomas account for approximately 40% of all pituitary adenomas and are an important cause of hypogonadism and infertility. The ultimate goal of therapy for prolactinomas is restoration or achievement of eugonadism through the normalization of ...
1997 Data on file   +627 more
core   +6 more sources

Prolactinomas [PDF]

open access: yesJAMA, 2021
Hyperprolactinemia, defined by a level of serum prolactin above the standard upper limit of normal range, is a common finding in clinical practice and prolactinomas are the main pathological cause. Prolactinomas lead to signs and symptoms of hormone oversecretion, such as galactorrhea and hypogonadism, as well as symptoms of mass effect, including ...
Pauline P, Huynh   +2 more
openaire   +4 more sources

Medical treatment of prolactinomas. [PDF]

open access: yesNature Reviews Endocrinology, 2011
Prolactinomas, the most prevalent type of neuroendocrine disease, account for approximately 40% of all pituitary adenomas. The most important clinical problems associated with prolactinomas are hypogonadism, infertility and hyposexuality.
A Barlier   +131 more
core   +5 more sources

Descriptive Epidemiology and Survival Analysis of Prolactinomas and Cushing’s Disease in Korea [PDF]

open access: yesEndocrinology and Metabolism, 2021
Background Only a few studies have established the epidemiology of prolactinoma and Cushing’s disease in Korea. Furthermore, the incidence of these disease are increasing than before associated with the development of technologies.
Jin Sun Park   +4 more
doaj   +1 more source

Approach to the Patient With Prolactinoma

open access: yesJournal of Clinical Endocrinology and Metabolism, 2023
Prolactinomas are the most common pituitary tumor histotype, with microprolactinomas being prevalent in women and macroprolactinomas in men. Hyperprolactinemia is among the most common causes of hypogonadotropic hypogonadism in both sexes, prompting ...
R. Auriemma   +5 more
semanticscholar   +1 more source

Surgery as first-line treatment for prolactinoma? Discussion of the literature and results of a consecutive series of surgically treated patients

open access: yesNeurosurgical review, 2023
Initial treatment for prolactinoma is usually conservative with dopamine agonists. However, the duration of treatment is often lifelong and can be associated with significant side effects.
M. Ottenhausen   +3 more
semanticscholar   +1 more source

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