Cabergoline Use and Pregnancy Outcomes: A Systematic Review. [PDF]
ABSTRACT Introduction Lack of available expert guidelines leads clinicians to interrupt cabergoline treatment upon confirmation of pregnancy and consider switching to bromocriptine, which is more commonly used during pregnancy but is poorly tolerated.
Otis AS+4 more
europepmc +2 more sources
Exploring retinal vessel density alterations in prolactinoma patients: Insights from OCTA imaging [PDF]
Purpose: To investigate microvascular changes in the macular and peripapillary area in prolactinoma patients by using optical coherence tomography angiography (OCTA). Design: A retrospective study.
Serife Ciloglu Hayat+3 more
doaj +2 more sources
MicroRNA networks in prolactinoma tumorigenesis: a scoping review [PDF]
Background Prolactinoma is the leading type of pituitary adenoma. Aside from the mass-like effect of prolactinoma, its hormonal effect is the main pathological cause of endocrine dysregulation and infertility.
Sevil Ghaffarzadeh Rad+2 more
doaj +2 more sources
A Comprehensive Neurological Study on the Relationship Between Prolactinoma and Alzheimer’s Disease [PDF]
Abstract Background Although most pituitary tumors are benign, functioning pituitary tumors are dangerous as they produce and deteriorate the endocrine hormones. Prolactinomas are one of these tumors that arise from lactotroph cells of the anterior pituitary, and they're about 40% of all pituitary adenomas.
Zid M, El‐Satar Y, Shahin A.
europepmc +2 more sources
Giant prolactinoma with progressive cranial settling and central herniation: a case report [PDF]
Background Giant prolactinoma (size > 4 cm) is a rare condition and accounts for less than 1% of pituitary adenomas. In even rarer cases, these lesions may involve craniocervical structures requiring surgical intervention. The present case is the largest
Taha Shahbazi+3 more
doaj +2 more sources
Transcriptomic analysis of the anti-tumor effects of leflunomide in prolactinoma [PDF]
Leflunomide’s anti-tumor effects have been investigated in various types of tumors; however, its impact on pituitary adenoma, particularly prolactinoma, is unclear.
Xiangdong Pei+6 more
doaj +2 more sources
miR-21-5p Targets PIK3R1 to Regulate the NF-κB Signaling Pathway, Inhibiting the Invasion and Progression of Prolactinoma. [PDF]
Prolactinomas (PRLs) are benign tumors with malignant characteristics that can invade the surrounding tissue structures and are challenging to treat. It has been reported that miR‐21‐5p expression in pituitary adenomas is correlated with tumor invasion and size. However, the mechanism of action of miR‐21‐5p in PRL remains unclear.
de Li M, Yang J, Wu X, Chen SS.
europepmc +2 more sources
Inhibiting MAPK14 showed anti-prolactinoma effect
Background The specific underlying pathogenesis of prolactinoma has not been clarified yet, to the best of our knowledge. p38 mitogen-activated protein kinase (MAPK) signaling including p38α MAPK (MAPK14), p38β (MAPK11), p38γ (MAPK12) and p38δ (MAPK13 ...
Qiao-yan Ding+6 more
doaj +1 more source
Adverse body composition and lipid parameters in patients with prolactinoma: a case-control study
Background Hyperprolactinaemia might cause adverse metabolic effects. The aim of our study was to compare parameters of body composition, glucose and lipid metabolism between untreated patients with prolactinoma and controls and to assess changes after ...
Anna Sophia Posawetz+7 more
doaj +1 more source
A 12-year-old male Yorkshire Terrier was presented because of decreased appetite. Physical examination revealed mammary gland swelling and galactorrhea. Contrast-enhanced computed tomographic scanning of the skull indicated an enlarged pituitary gland, compatible with a pituitary tumor. The serum prolactin concentration was markedly elevated. One week
Cosio, Cristina+6 more
openaire +5 more sources