Results 41 to 50 of about 7,977 (217)

Menstrual cycle abnormalities in patients with prolactinoma and drug-induced hyperprolactinemia

Indian Journal of Endocrinology and Metabolism, 2017
Background and Objective: Hyperprolactinemia affects the reproductive endocrine axis; however, the degree of dysfunction may vary depending on etiology.
Bindu Kulshreshtha, Isha Pahuja, Deepak Kothari, Indu Chawla, Neera Sharma, Shikha Gupta, Anuja Mittal   +6 more
doaj   +1 more source

Parkinson's disease under dopamine replacement therapy as a human framework for studying addiction‐relevant mechanisms

Psychiatry and Clinical Neurosciences, EarlyView.
Addiction is a chronic relapsing condition characterized by compulsive reward seeking and impaired behavioral control, associated with major individual and societal burden. Mechanistic investigation in humans remains constrained by ethical limitations, uncontrolled exposure histories, and ecological confounds.
Vanessa Fleury, Elvira Pirondini, Damien Benis, Tiffany Corbet, Gabriel Thorens, Christian Lüscher, Paul Krack   +6 more
wiley   +1 more source

Wogonin inhibits the proliferation of prolactinoma through the PI3K/AKT signaling pathway

Frontiers in Pharmacology
ObjectivesThis investigation sought to explore the inhibitory impact of wogonin on prolactinoma and elucidate its underlying mechanisms through network pharmacology, molecular docking (MD), and molecular biology experiments.MethodsTarget identification ...
Zhiyong Du, Zhiyong Du, Zhiyong Du, Zhiyong Du, Cuiping Sun, Cuiping Sun, Cuiping Sun, Cuiping Sun, Jiawei Wu, Jiawei Wu, Hongwei Gao, Hongwei Gao, Hongwei Gao, Hongwei Gao, Jialong Wu, Jialong Wu, Jialong Wu, Jialong Wu, You Zhou, You Zhou, You Zhou, You Zhou, Xuechao Wu, Xuechao Wu, Liping Shen, Liping Shen, Qing Wang, Qing Wang, Qing Wang, Qing Wang   +29 more
doaj   +1 more source

A Novel Case of Spontaneous Coronary Artery Dissection During Cabergoline Therapy for Prolactinoma

JACC: Case Reports, 2020
We present a case of spontaneous coronary artery dissection associated with cabergoline treatment for prolactinoma. A 31-year-old woman with history of hypertension and prolactinoma, treated with cabergoline, presented with chest pain.
Shinichiro Ikeda, MD, Jeffrey Le, MD, Shivani Verma, MD, Benjamin A. Youdelman, MD   +3 more
doaj   +1 more source

Protein Lactylation in Cancer: From Mechanisms to Therapy

MedComm, Volume 7, Issue 11, November 2026.
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang, Ping Hu, Shun Wang, Xide Zhang, Ziran Ye, Shengqiang Chen, Fu Gao, Yuanyuan Chen, Yanyong Yang   +8 more
wiley   +1 more source

The recurrence of prolactinoma after withdrawal of dopamine agonist: a systematic review and meta-analysis

BMC Endocrine Disorders, 2021
Background Prolactinoma is the major cause of hyperprolactinemia, and dopamine agonists (DAs) are generally the first-line treatment for them. Several studies have reviewed the recurrent rate of hyperprolactinemia after DAs withdrawal.
Yunzhi Zou, Depei Li, Jiayu Gu, Siyu Chen, Xia Wen, Jiajun Dong, Xiaobing Jiang   +6 more
doaj   +1 more source

Human biomarker navigator

iMeta, Volume 5, Issue 5, October 2026.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Prolactinoma in a Dog [PDF]

Veterinary Pathology, 2017
A 12-year-old male Yorkshire Terrier was presented because of decreased appetite. Physical examination revealed mammary gland swelling and galactorrhea. Contrast-enhanced computed tomographic scanning of the skull indicated an enlarged pituitary gland, compatible with a pituitary tumor. The serum prolactin concentration was markedly elevated.
Cosio, Cristina, Sartori, Elena, Garatti, Marcello, Luccardini, Lorenzo, Grinwis, G. C. M., Kooistra, Hans S., Fracassi, Federico   +6 more
openaire   +5 more sources

A giant invasive macroprolactinoma with recurrent nasal bleeding as the first clinical presentation: case report and review of literature

BMC Endocrine Disorders, 2023
Background Giant prolactinoma (> 4 cm in dimension) is a rare disorder. Invasive macroprolactinoma has the potential to cause base of skull erosion and extend into the nasal cavity or even the sphenoid sinus.
Danting Li, Yan Wang, Huiwen Tan, Peiqiong Luo, Yerong Yu   +4 more
doaj   +1 more source

Hypogonadotropic Hypogonadism Before and After Transsphenoidal Surgery for Non‐Functioning Pituitary Adenoma

Clinical Endocrinology, Volume 105, Issue 4, Page 442-451, October 2026.
ABSTRACT Objective The effect of transsphenoidal surgery (TSS) on the hypothalamic‐pituitary‐gonadal (HPG) axis in patients with non‐functioning pituitary adenomas (NFPA) is underexplored, especially in women. Our aim was to investigate the HPG axis function before and after TSS, its association with quality of life (QoL), and to identify factors that ...
Victor Hantelius, Gudmundur Johannsson, Sofie Jakobsson, Erik Thurin, Tobias Hallen, Thomas Skoglund, Oskar Ragnarsson   +6 more
wiley   +1 more source