Results 51 to 60 of about 10,516 (266)
ABSTRACT Introduction Many survivors of childhood brain tumors face long‐term adverse health outcomes like obesity. Uncertainties surround the effect of interventions to manage obesity‐related outcomes in survivors of childhood brain tumors. The goal of this updated systematic review and meta‐analysis was to provide the best estimate of the treatment ...
David Hart +11 more
wiley +1 more source
Hypogonadotropic hypogonadism is a common finding in patients who are diagnosed with a prolactinoma. It can be accompanied by the presence of other pituitary hormone deficits, including secondary adrenal insufficiency and central hypothyroidism.
Lakshmi P Menon, Dinesh Edem
doaj +1 more source
Pituitary Tumour Apoplexy as Cause of Death of Simonetta Vespucci, the Venus by Botticelli
A reassessment of Simonetta Vespucci, muse of Sandro Botticelli, attributes her long‐mysterious death to a pituitary adenoma. Clinical reinterpretation of historical accounts suggests tumour expansion led to sellar destruction, severe haemorrhage, and pulmonary complications, offering a coherent medical explanation for her sudden death at twenty‐three.
Domiziana Nardelli +3 more
wiley +1 more source
ABSTRACT Optic neuritis is an acute inflammatory disease that can cause acute visual loss. We present a case of a 22‐year‐old female in postpartum with acute headache, retroocular pain, and bilateral amaurosis. Orbit MRI revealed inflammatory changes in both neurovascular optical bundles.
Jose Luis Rojas‐Oviedo +5 more
wiley +1 more source
An uncommon cause of osteoporosis
Osteoporosis in the younger age group is an important cause of morbidity. Prolactinoma is an uncommon but reversible cause of osteoporosis. The main mechanisms of osteoporosis in prolactinoma are reduced osteoblast activity and hypogonadism. A high index
Rohit Barnabas +5 more
doaj +1 more source
Additional file 5: Figure S4. AS events in SF3B1 mutant human prolactinoma and MRI scans of the estradiol-induced prolactinoma model. (A) Volcano plot showing the differential alternative splicing events in SF3B1 mutant vs.
Jing Guo (102972) +7 more
core +1 more source
Continuous outcome estimation in N‐of‐1 trials for accelerated decision‐making
Abstract Objective N‐of‐1 trials aim to determine the therapeutic effect for a single individual. This individualized approach necessitates collecting multiple data points over time through repeated alternating periods of active treatment and a comparator or control condition.
Victoria Defelippe +5 more
wiley +1 more source
Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret +5 more
wiley +1 more source
Los prolactinomas son uno de los principales tipos de adenomas hipofisarios constituyendo hasta un 50% de dichos tumores, con un gran impacto sobre la salud de esta población, derivado de sus efectos clínicos: 1) efectos hormonales por hiperprolactinemia
Fuentes Garzón, Nubia Maribel
core +1 more source
Background: Pituitary disorders spectrum includes a wide variety of diseases.This study aimed at a comprehensive description of such disorders for patients from Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC) in Basrah (Southern Iraq)
Abbas Ali Mansour +11 more
doaj +1 more source

