Cabergoline Treatment in Invasive Giant Prolactinoma [PDF]
Patients with invasive giant prolactinoma suffer from a constellation of symptoms including headache, blurred vision, lethargy, and sexual dysfunction. Cabergoline, a potent dopamine agonist, is a known medication prescribed for the treatment of invasive
Mussa Almalki
exaly +8 more sources
Aggressive giant prolactinoma: a case report [PDF]
Background Managing treatment-resistant aggressive giant prolactinoma can be challenging, as the diagnosis is often complex, and treatment beyond dopamine agonists, surgery, and radiotherapy is limited.
Marisa Khatijah Borhan +1 more
doaj +4 more sources
Giant Prolactinoma Causing Hydrocephalus and Intracranial Hypertension as First Manifestations of Multiple Endocrine Neoplasia Type 1 [PDF]
Context: Overall, giant prolactinomas are rare tumors (4%), especially those larger than 60 mm (1%). Despite the predominance of macroadenoma documented in multiple endocrine neoplasia type 1 (MEN1)-related prolactinoma, only three giant prolactinoma ...
Naiara Castelo Branco Dantas +2 more
exaly +4 more sources
A novel germline CDH23 variant as a likely cause of an ultra-giant prolactinoma [PDF]
Giant prolactinomas are defined as pituitary adenomas (PAs) ≥ 4 cm with plasma prolactin level > 1000 ng/ml with no other co-secretory component. The reasons for development of giant prolactinomas are not clear but genetics play an important pathogenic ...
Avaniyapuram Kannan Murugan +2 more
exaly +3 more sources
Beat the giant: case of a giant prolactinoma during pregnancy on cabergoline [PDF]
Giant prolactinomas are a rare entity; during pregnancy, the risk for complications associated with these tumors is higher. Here, we report a case of a young woman who had an invasive, giant prolactinoma post resection with residual disease who became ...
Wael M Almistehi, Mussa H Almalki
doaj +5 more sources
Giant Prolactinoma Presenting with Neck Pain and Structural Compromise of the Occipital Condyles [PDF]
Prolactinomas are the most common form of endocrinologically active pituitary adenoma; they account for ∼ 45% of pituitary adenomas encountered in clinical practice. Giant adenomas are those > 4 cm in diameter.
Laurence Katznelson +2 more
exaly +4 more sources
A case of giant prolactinoma and pituitary hemorrhage with the late recovery of pituitary function: A case report [PDF]
Hypogonadotropic hypogonadism is a common finding in patients who are diagnosed with a prolactinoma. It can be accompanied by the presence of other pituitary hormone deficits, including secondary adrenal insufficiency and central hypothyroidism.
Lakshmi P Menon, Dinesh Edem
doaj +2 more sources
Giant Prolactinoma: Challenges in Management. [PDF]
Prolactinomas are the most common form of pituitary adenomas, 90% of which are microprolactinomas measuring 4 cm with a serum prolactin level of >1000 ng/mL. We report a case of giant prolactinoma causing optic nerve compression that initially responded well to cabergoline and later developed intratumoral hemorrhage requiring transsphenoidal resection ...
Sharma S, Acharya M, Sherpa C.
europepmc +4 more sources
Foster Kennedy syndrome secondary to a giant prolactinoma with a remarkable response to cabergoline [PDF]
Pituitary adenomas are intracranial neoplasms, usually demonstrating a benign phenotype. We present the case of 21-year-old male with an 18-month history of reduced visual function (acuity and field) in the left eye.
Usama Kanj +5 more
doaj +2 more sources
Giant prolactinoma with progressive cranial settling and central herniation: a case report [PDF]
Background Giant prolactinoma (size > 4 cm) is a rare condition and accounts for less than 1% of pituitary adenomas. In even rarer cases, these lesions may involve craniocervical structures requiring surgical intervention. The present case is the largest
Taha Shahbazi +3 more
doaj +2 more sources

