Results 41 to 50 of about 218,733 (151)

Update in Pathogenesis, Diagnosis, and Therapy of Prolactinoma

, 2022
SIMPLE SUMMARY: This review updates recent advances in the pathogenesis, diagnosis, and therapy of prolactinoma. Prolactinomas, comprising 30–50% of all pituitary neuroendocrine tumors, frequently occur in females aged 20 to 50 and cause hypogonadism and
Nishiyama, Mitsuru, Iwasaki, Yasumasa, Mitsuru Nishiyama, Yasumasa Iwasaki, Fukuhara, Noriaki, Noriaki Fukuhara   +5 more
core   +1 more source

Very Long‐Term Follow‐Up of Multidimensional Health‐Related Quality of Life After Endoscopic Endonasal Surgery for Pituitary Adenomas: A Prospective Cohort Study

Head &Neck, Volume 48, Issue 4, Page 1088-1096, April 2026.
ABSTRACT Background To evaluate postoperative health‐related quality of life (HRQoL) for pituitary adenoma patients, multidimensional assessment is important. Available data is limited on long‐term follow‐up. Methods Prospectively, 52 nonfunctioning (NFA) and functioning (FA) pituitary adenoma patients were included.
Gonneke E. Joustra, Nathalie F. van Rhee, Marc C. den Heijer, Astrid G. W. Korsten‐Meijer, Robert A. Feijen, György B. Halmos, Jos M. A. Kuijlen, Karin M. Vermeulen   +7 more
wiley   +1 more source

The importance of measuring prolactin prior to surgical management of a pituitary lesion: An illustrative case

Radiology Case Reports, 2023
The characterization of sellar and suprasellar lesions is reliant on patient presentation, medical imaging, and hormone profiling. Prolactinomas are the most common type of functional pituitary adenomas, accounting for up to 57%.
Nikita Ollen-Bittle, MSc, Donald Lee, MD, Alain Proulx, MD, MSc, Neil Duggal, MD, MSc, Stan H.M. Van Uum, MD, PhD   +4 more
doaj   +1 more source

Adrenal Crisis Induced by Zoledronic Acid in Two Patients With Hypopituitarism: A Case Report and Literature Review

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Adrenal insufficiency (AI) is characterized by inadequate steroid hormone production and is frequently a consequence of hypopituitarism, which is also associated with increased risk of osteoporosis due to deficiencies in growth hormone, gonadotropins, and other pituitary hormones.
Abrar Mohammed AlFaifi, Wael Mohammad AlMistehi, Osamu Isozaki   +2 more
wiley   +1 more source

Clinical and Genetic Spectrum of Large AIP Deletions

Human Mutation, Volume 2026, Issue 1, 2026.
Familial isolated pituitary adenoma (FIPA) accounts for approximately 2%–5% of all pituitary adenomas, with inactivating variants of the aryl hydrocarbon receptor‐interacting protein (AIP) gene representing the most frequent known genetic cause.
Tea Shehu Kolnikaj, Maren Ruka, Artur Xhumari, Anila Babameto-Laku, Athanasios Siolos, Panagiotis Alexandros Drakos, Kesson Magid, Thomas O. Millner, Robert D. Murray, Marinella Tzanela, Dragana Miljić, Arlinda Ramaj, Paul Benjamin Loughrey, Stelios Tigas, Márta Korbonits, Neetu Rawal   +15 more
wiley   +1 more source

Molecular Basis of Aggressiveness in Pituitary Adenomas and Its Association With the Immune Microenvironment

International Journal of Genomics, Volume 2025, Issue 1, 2025.
Background: Pituitary adenomas (PAs) are common intracranial tumors, and their aggressive phenotype exhibits a poor prognosis. We aimed to explore the aggressive feature of PAs and discover novel diagnostic markers. Method: The datasets of GSE260487 and GSE169498, which contained invasive and noninvasive samples, were downloaded from the Gene ...
Xiaoyan Chen, Jingnan Wang, Qianqian Guo, Minghua Ren   +3 more
wiley   +1 more source

Advancements in Molecular Diagnosis and Pharmacotherapeutic Strategies for Invasive Pituitary Adenomas

Immunity, Inflammation and Disease, Volume 12, Issue 12, December 2024.
ABSTRACT Background The overwhelming majority of pituitary tumors consist of pituitary adenomas (PAs), which have recently also been termed pituitary neuroendocrine tumors (PitNETs). Clinically significant PAs occur in approximately one in every 1000 individuals, while other types of pituitary tumors, such as craniopharyngiomas and pituicytomas, are ...
Dingkai Xu, Ling Wang, Maohua Zheng
wiley   +1 more source

AIP variant causing familial prolactinoma [PDF]

, 2020
Pathogenic variants in the aryl hydrocarbon receptor-interacting protein (AIP) gene are increasingly recognised as a cause of familial isolated pituitary adenoma. AIP-associated tumours are most commonly growth hormone (GH) producing.
Magid, K, Carty, DM, Magid, Kesson, Drummond, RS, Owens, M, Carty, David M., Owens, Martina, Ward, Rebecca, Korbonits, Márta, Collier, David, Collier, D, Korbonits, M, Harte, Rachael, Drummond, Russell S., Ward, R, Harte, R   +15 more
core   +1 more source

Visual morbidity in macroprolactinoma: A retrospective cohort study

Clinical Endocrinology, Volume 101, Issue 6, Page 648-658, December 2024.
Abstract Objective The management of visual field damage in patients with macroprolactinomas is a major therapeutic challenge. We aimed to study the visual morbidity associated with macroprolactinoma and its outcomes following medical and surgical treatment. We aimed to identify predictors of visual recovery. Methods We retrospectively reviewed patient'
Yaron Rudman, Hadar Duskin‐Bitan, Hiba Masri‐Iraqi, Amit Akirov, Ilan Shimon   +4 more
wiley   +1 more source

Efficacy and safety of endoscopic transsphenoidal resection for prolactinoma: a retrospective multicenter case-series [PDF]

, 2023
Background: Endoscopic transsphenoidal surgery (ETSS) for prolactinoma is reserved for dopamine agonist (DA) resistance, intolerance, or apoplexy. High remission (overall 67%, microprolactinoma up to 90%), low recurrence (5-20%) rates highlighted that ...
Bakker, L.E.H., White, T.G., Pelsma, I.C.M., Prevedello, D.M., Zandbergen, I.M., Ghalib, L.M., Biermasz, N.R., Furth, W.R.V., Verstegen, M.J.T., Dehdashti, A.R., Huntoon, K.M.   +10 more
core   +1 more source