Results 51 to 60 of about 218,733 (151)
Introduction Pituitary tumors from lactotrope cells account for about 40% of all functioning pituitary cancers. Men tend to present with a larger, more invasive and rapid growth prolactinomas than women, possibly because hypogonadism features are less ...
Shadin Alkatari, Naji Aljohani
doaj +2 more sources
Macroprolactinoma with an atypical course
Prolactinomas are among the most common pituitary adenomas. The typical symptoms of hyperprolactinemia associated with a prolactinomaprimarily include symptoms of hypogonadism resulting from the suppression of the hypothalamic–pituitary–gonadal axis.In ...
Elżbieta Andrysiak-Mamos +3 more
doaj +1 more source
Identification of a novel somatic mutation of POU6F2 by whole‐genome sequencing in prolactinoma
Background Pituitary adenomas (PAs) are one of the most common intracranial tumors; approximately half of PAs are prolactin (PRL)‐secreting PAs (prolactinomas). The genetic alterations prevalent in prolactinomas are unknown.
Yazhou Miao +6 more
doaj +1 more source
Peptide receptor radionuclide therapy for aggressive pituitary tumors: a monocentric experience
In aggressive pituitary tumors (PT) showing local invasion or growth/recurrence despite multimodal conventional treatment, temozolomide (TMZ) is considered a further therapeutic option, while little data are available on peptide receptor radionuclide ...
G Giuffrida +10 more
doaj +1 more source
The cavernous sinus: An anatomic study with clinical implication
This manuscript examines the gross anatomy of the region and highlights important surgical implications drawn from these as well as previously published studies. Herein, I perform a review of the historical scientific, anatomic, clinical, and surgical literature and additionally perform and describe cadaveric dissections revealing novel details about ...
Myles L. Pensak
wiley +1 more source
Phosphorylation of PBK at Thr9 by CDK5 correlates with invasion of prolactinomas
The level of pPBK‐T9 is highly expressed in invasive PitNETs, CDK5 could promote the phosphorylation of PBK‐T9 through the p38 MAPK signaling pathway to promote cell proliferation and EMT progression. we revealed that this signaling axis in PitNETs, CDK5/PBK/p38 MAPK, promoted the tumorigenesis of PitNETs.
Qiuyue Fang +5 more
wiley +1 more source
Atypical Giant Suprasellar Prolactinoma Presenting With Visual Field Changes in the Absence of Symptoms of Hyperprolactinemia [PDF]
Prolactinomas are benign tumors that make up the majority of all pituitary adenoma cases and present most commonly in women. Prolactinomas presenting in adolescents and children, however, are extremely rare.
Mo, Jun Q +7 more
core +1 more source
Idiopathic Granulomatous Mastitis
Idiopathic granulomatous mastitis (IGM) is a rare, benign inflammatory disorder of the breast that is often underrecognized. The exact etiology and pathophysiology are unknown, but milk stasis is felt to play a role. Classically, this condition is noninfectious, but many cases are noted to be associated with Corynebacterium species.
Christina Dilaveri +6 more
wiley +1 more source
Purpose Giant prolactinomas, which have extremely large sizes and high prolactin (PRL) values, are rarely seen. Although medical therapy is effective, surgical treatment is more frequently applied due to slightly lower response rates and compression ...
Hakyemez, Bahattin
core +1 more source
Cabergoline Therapy in Giant Prolactinoma With Secondary Apoplexy: A Case Report
Pituitary apoplexy (PA) is a rare, potentially life-threatening clinical syndrome resulting from acute infarction or hemorrhage of the pituitary gland1.
Paul Kay; Kimberly Winges
core

