Results 51 to 60 of about 218,733 (151)

Obstructive Hydrocephalus, Fifth Nerve and Hypothalamus Involvement: Acute Presentation of a Giant Prolactinoma

open access: yesClinical Medicine Insights: Case Reports, 2012
Introduction Pituitary tumors from lactotrope cells account for about 40% of all functioning pituitary cancers. Men tend to present with a larger, more invasive and rapid growth prolactinomas than women, possibly because hypogonadism features are less ...
Shadin Alkatari, Naji Aljohani
doaj   +2 more sources

Macroprolactinoma with an atypical course

open access: yesEndokrynologia Polska
Prolactinomas are among the most common pituitary adenomas. The typical symptoms of hyperprolactinemia associated with a prolactinomaprimarily include symptoms of hypogonadism resulting from the suppression of the hypothalamic–pituitary–gonadal axis.In ...
Elżbieta Andrysiak-Mamos   +3 more
doaj   +1 more source

Identification of a novel somatic mutation of POU6F2 by whole‐genome sequencing in prolactinoma

open access: yesMolecular Genetics & Genomic Medicine, 2019
Background Pituitary adenomas (PAs) are one of the most common intracranial tumors; approximately half of PAs are prolactin (PRL)‐secreting PAs (prolactinomas). The genetic alterations prevalent in prolactinomas are unknown.
Yazhou Miao   +6 more
doaj   +1 more source

Peptide receptor radionuclide therapy for aggressive pituitary tumors: a monocentric experience

open access: yesEndocrine Connections, 2019
In aggressive pituitary tumors (PT) showing local invasion or growth/recurrence despite multimodal conventional treatment, temozolomide (TMZ) is considered a further therapeutic option, while little data are available on peptide receptor radionuclide ...
G Giuffrida   +10 more
doaj   +1 more source

The cavernous sinus: An anatomic study with clinical implication

open access: yesLaryngoscope Investigative Otolaryngology, Volume 9, Issue 2, April 2024.
This manuscript examines the gross anatomy of the region and highlights important surgical implications drawn from these as well as previously published studies. Herein, I perform a review of the historical scientific, anatomic, clinical, and surgical literature and additionally perform and describe cadaveric dissections revealing novel details about ...
Myles L. Pensak
wiley   +1 more source

Phosphorylation of PBK at Thr9 by CDK5 correlates with invasion of prolactinomas

open access: yesCNS Neuroscience &Therapeutics, Volume 30, Issue 2, February 2024.
The level of pPBK‐T9 is highly expressed in invasive PitNETs, CDK5 could promote the phosphorylation of PBK‐T9 through the p38 MAPK signaling pathway to promote cell proliferation and EMT progression. we revealed that this signaling axis in PitNETs, CDK5/PBK/p38 MAPK, promoted the tumorigenesis of PitNETs.
Qiuyue Fang   +5 more
wiley   +1 more source

Atypical Giant Suprasellar Prolactinoma Presenting With Visual Field Changes in the Absence of Symptoms of Hyperprolactinemia [PDF]

open access: yes, 2021
Prolactinomas are benign tumors that make up the majority of all pituitary adenoma cases and present most commonly in women. Prolactinomas presenting in adolescents and children, however, are extremely rare.
Mo, Jun Q   +7 more
core   +1 more source

Idiopathic Granulomatous Mastitis

open access: yesThe Breast Journal, Volume 2024, Issue 1, 2024.
Idiopathic granulomatous mastitis (IGM) is a rare, benign inflammatory disorder of the breast that is often underrecognized. The exact etiology and pathophysiology are unknown, but milk stasis is felt to play a role. Classically, this condition is noninfectious, but many cases are noted to be associated with Corynebacterium species.
Christina Dilaveri   +6 more
wiley   +1 more source

Comparison of the effects of medical and surgical treatments in giant prolactinoma: A single-center experience

open access: yes, 2021
Purpose Giant prolactinomas, which have extremely large sizes and high prolactin (PRL) values, are rarely seen. Although medical therapy is effective, surgical treatment is more frequently applied due to slightly lower response rates and compression ...
Hakyemez, Bahattin
core   +1 more source

Cabergoline Therapy in Giant Prolactinoma With Secondary Apoplexy: A Case Report

open access: yes, 2022
Pituitary apoplexy (PA) is a rare, potentially life-threatening clinical syndrome resulting from acute infarction or hemorrhage of the pituitary gland1.
Paul Kay; Kimberly Winges
core  

Home - About - Disclaimer - Privacy