Results 21 to 30 of about 218,733 (151)

Giant prolactinomas in men: efficacy of cabergoline treatment

Clinical Endocrinology, 2003
Summaryobjective The term ‘giant prolactinoma’ can be used for tumours larger than 4 cm in diameter and/or with massive extrasellar extension. Cabergoline (CAB), a long‐lasting dopamine agonist (DA), safe and well tolerated, is effective in normalizing PRL levels and inducing tumour shrinkage in micro‐ and macroprolactinomas.
Corsello, Salvatore Maria, Ubertini, G, Altomare, M, Lovicu, Rm, Migneco, Mg, Rota, Carlo Antonio, Colosimo, Cesare   +6 more
openaire   +4 more sources

Giant prolactinomas in women [PDF]

European Journal of Endocrinology, 2014
ObjectiveTo characterise distinctive clinical features of giant prolactinomas in women.DesignA multicentre, retrospective case series and literature review.MethodsWe collected data from 15 female patients with a pituitary tumour larger than 4 cm and prolactin levels above 1000 μg/l and identified 19 similar cases from the literature; a gender-based ...
Delgrange, Etienne, Raverot, Gerald, Bex, Marie, Burman, Pia, Decoudier, Bénédicte, Devuyst, France, Feldt-Rasmussen, Ulla, Andersen, Marianne, Maiter, Dominique   +8 more
openaire   +4 more sources

Giant prolactinomas: the therapeutic approach [PDF]

Clinical Endocrinology, 2013
AbstractBackgroundGiant prolactinomas are an unusual subset of macroprolactinomas and are more commonly found in men. The goal of this review is to propose a giant prolactinoma definition and discuss the available therapeutic options for biochemical and tumour volume control.MethodsA comprehensive search of all published studies was performed ...
Aline B, Moraes, Cintia Marques dos Santos, Silva, Leonardo, Vieira Neto, Mônica R, Gadelha   +3 more
openaire   +2 more sources

Pronounced hyperostosis frontalis interna and co‐occurring lesions in the skull base suggestive of a pituitary tumor in a woman from medieval Germany

International Journal of Osteoarchaeology, Volume 33, Issue 6, Page 1095-1100, November/December 2023., 2023
Abstract Hyperostosis frontalis interna (HFI) is an osseous overgrowth characterized by symmetrical, irregular bone apposition on the internal table of the frontal bone, which preferentially occurs in females. In 1719, Morgagni described the condition as one sign of a triad comprising HFI, hirsutism, and obesity (Morgagni's syndrome).
Stefan Flohr, Carsten Witzel, Uwe Kierdorf   +2 more
wiley   +1 more source

Regulation of long noncoding RNAs in the pathogenesis and clinical implications of pituitary adenomas

Immunity, Inflammation and Disease, Volume 11, Issue 10, October 2023., 2023
Abstract Background Pituitary adenoma (PA) is a type of tumor that develops in the sella turcica and is one of the most frequent intracranial tumors. It belongs to a type of adenoma derived from a single clone of cells in the pituitary gland. PA ranks third among all intracranial tumors, following only gliomas and meningioma.
Ling Wang, Dingkai Xu
wiley   +1 more source

Hemoglobin decline as a signal for hyperprolactinemia onset prior to prolactinoma diagnosis in hypogonadal men

Andrology, Volume 11, Issue 7, Page 1398-1407, October 2023., 2023
Abstract Background Men harboring prolactinomas frequently suffer from central hypogonadism with secondary anemia. They present insidious and nonspecific symptoms of hypogonadism, making it difficult to diagnose the disease and determine its duration. The result is a delay in diagnosis, which may have harmful hormonal and metabolic consequences.
Yaron Rudman, Hadar Duskin‐Bitan, Ilan Richter, Gloria Tsvetov, Hiba Masri‐Iraqi, Amit Akirov, Ilan Shimon   +6 more
wiley   +1 more source

supplementary data for study 'Giant prolactinoma in childhood and adolescents: a single-center experience and systematic review'.

, 2022
This is supplementary information to study 'Giant prolactinoma in childhood and adolescents: a single-center experience and systematic review'
Saba Memon (10040513), Sandeep Kumar (12031757)   +1 more
core   +1 more source

Pituitary metastasis from renal cell carcinoma presenting with significant hyperprolactinemia, case report

Clinical Case Reports, Volume 11, Issue 9, September 2023., 2023
Key Clinical Message Kidney metastasis to the pituitary gland can cause hyperprolactinemia even above 250 ng/mL. Although the treatment of metastasis is palliative, surgical decompression could play a major role in the recovery of symptoms and improve quality of life.
Ali Mazar‐Atabaki, Omid Mohamadzadeh, Seyed Mousa Sadrehosseini, Azin Tabari, Mehdi Zeinalizadeh   +4 more
wiley   +1 more source

Giant Prolactinomas [PDF]

Neuroendocrinology, 2018
Prolactin-secreting adenomas (prolactinomas) are the most common secreting adenomas of the pituitary. Microprolactinomas (diameter <10 mm) are frequently diagnosed in women, whereas macroprolactinomas (maximum diameter ≥10 mm) are generally seen in men. Most macroprolactinomas measure between 10 and 40 mm.
openaire   +2 more sources

Identifying hormones and other perioperative risk factors for postoperative delirium after endoscope‐assisted transsphenoidal pituitary adenoma resection: A retrospective, matched cohort study

Brain and Behavior, Volume 13, Issue 7, July 2023., 2023
We investigated the potential perioperative risk factors for postoperative delirium in pituitary adenoma patients treated by endoscope‐assisted transsphenoidal surgery. We found that lower IGF‐1 and CRH levels were tightly associated with postdelirium and high levels of blood glucose (GLU) after surgery.
Jin Liu, Jinyu Qian, Xia Wang, Jie Lin, Sunyan Yang, Rong Hu, Jishu Xian, Hua Feng, Yujie Chen, Binbin Tan   +9 more
wiley   +1 more source