Results 61 to 70 of about 7,708 (214)
An uncommon cause of osteoporosis
Journal of Family Medicine and Primary Care, 2018 Osteoporosis in the younger age group is an important cause of morbidity. Prolactinoma is an uncommon but reversible cause of osteoporosis. The main mechanisms of osteoporosis in prolactinoma are reduced osteoblast activity and hypogonadism. A high index
Rohit Barnabas +5 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Optic neuritis is an acute inflammatory disease that can cause acute visual loss. We present a case of a 22‐year‐old female in postpartum with acute headache, retroocular pain, and bilateral amaurosis. Orbit MRI revealed inflammatory changes in both neurovascular optical bundles.
Jose Luis Rojas‐Oviedo +5 more
wiley +1 more source
Parathormone-Related Peptide Is Not Associated with Bone Mineral Density in Eugonadal Prolactinoma
Endocrinology Research and Practice, 2023 Objective: One of many theories for the cause of osteoporosis in prolactinoma is the increased level of the parathyroid hormone-related peptide. We aimed to assess the parathyroid hormone-related pep- tide levels and its potential effects on bone mineral
Arzu Okyar Baş +2 more
doaj
Annals of Medicine, 1998 The objectives of the treatment of hyperprolactinaemia are to suppress excessive hormone secretion and its clinical consequences, to remove tumour mass, to preserve the residual pituitary function and to prevent disease recurrence or progression. Prior to the advent of pharmacotherapy, therapy usually consisted of surgical resection and/or pituitary ...
COLAO, ANNAMARIA +2 more
openaire +3 more sources
Continuous outcome estimation in N‐of‐1 trials for accelerated decision‐making
Epilepsia, Volume 67, Issue 5, Page 2254-2269, May 2026.Abstract Objective N‐of‐1 trials aim to determine the therapeutic effect for a single individual. This individualized approach necessitates collecting multiple data points over time through repeated alternating periods of active treatment and a comparator or control condition.
Victoria Defelippe +5 more
wiley +1 more source
Anti-EGFL7 antibodies inhibit rat prolactinoma MMQ cells proliferation and PRL secretion
Open Chemistry, 2018 Prolactinoma is the most frequently diagnosed pituitary tumors. Dopamine agonists (DAs) are recognized as first-line therapy; however, approximately 10% patients will develop resistance to DAs therapy.
Liu Qian +5 more
doaj +1 more source
F1000Research, 2018 Background: Pituitary disorders spectrum includes a wide variety of diseases.This study aimed at a comprehensive description of such disorders for patients from Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC) in Basrah (Southern Iraq)
Abbas Ali Mansour +11 more
doaj +1 more source
Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders
Andrology, Volume 14, Issue 4, Page 1002-1016, May 2026.Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret +5 more
wiley +1 more source
Aggressive and Malignant Prolactinomas [PDF]
Neuroendocrinology, 2019 Prolactin-secreting tumors (prolactinomas) represent the most common pituitary tumor type, accounting for 47–66% of functional pituitary tumors. Prolactinomas are usually benign and controllable tumors as they express abundant levels of dopamine type 2 receptor (D2), and can be treated with dopaminergic drugs, effectively reducing prolactin levels and ...
Olarescu, Nicoleta Cristina +7 more
openaire +6 more sources