Results 71 to 80 of about 7,708 (214)

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

Advanced Science, Volume 13, Issue 24, 27 April 2026.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su, Li Ma, Xi Xiong, Jun‐hua Meng, Qi Wu, Yu Zhang, Shu‐guang Dong, Yue‐fei Wang, Jin‐hu Wu, Qing‐yuan Zeng, Hong‐feng Zhang, Li‐li Li, Liang Meng, Min Peng, Xiao‐dong Huang, Li‐quan Wu, Xiong Wang   +16 more
wiley   +1 more source

Very Long‐Term Follow‐Up of Multidimensional Health‐Related Quality of Life After Endoscopic Endonasal Surgery for Pituitary Adenomas: A Prospective Cohort Study

Head &Neck, Volume 48, Issue 4, Page 1088-1096, April 2026.
ABSTRACT Background To evaluate postoperative health‐related quality of life (HRQoL) for pituitary adenoma patients, multidimensional assessment is important. Available data is limited on long‐term follow‐up. Methods Prospectively, 52 nonfunctioning (NFA) and functioning (FA) pituitary adenoma patients were included.
Gonneke E. Joustra, Nathalie F. van Rhee, Marc C. den Heijer, Astrid G. W. Korsten‐Meijer, Robert A. Feijen, György B. Halmos, Jos M. A. Kuijlen, Karin M. Vermeulen   +7 more
wiley   +1 more source

Patients With Pituitary Neuroendocrine Tumours Requiring Neurosurgery –Who Is Referring Them?

Clinical Endocrinology, Volume 104, Issue 4, Page 352-361, April 2026.
ABSTRACT Objective Patients living with pituitary neuroendocrine tumours (PitNETs) present with a spectrum of clinical manifestations and often follow a circuitous route to diagnosis, resulting in diagnostic delays. The objective of this study is to identify and report the various sources of referrals for patients who underwent pituitary resection for ...
Doua S. Ahmed, Brian Herron, Stephen Cooke, Philip Weir, Jane Evanson, Estelle G. Healy, Karen R. Mullan, Stephanie G. Craig, Jacqueline A. James, Márta Korbonits, Steven J. Hunter, Paul Benjamin Loughrey   +11 more
wiley   +1 more source

NR3C1 Modulates Wnt Signalling to Influence the Invasiveness and Immune Features of Nonfunctioning Invasive Pituitary Adenomas

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Pituitary adenomas (PAs) are common intracranial tumours, and invasiveness in nonfunctioning invasive pituitary adenomas (NIPAs) predicts poor prognosis. The molecular mechanisms driving this phenotype remain unclear. This study explored the role of nuclear receptor subfamily 3 group C member 1 (NR3C1) in NIPA invasiveness and its regulation ...
Xiaoping Wang, Jinfeng Zhang, Tao Jiang, Zhijun Yang, Yu Zhang, Pinan Liu, Yuanxiang Lin   +6 more
wiley   +1 more source

The emerging role of chemokines and chemokine receptors in the biological and clinical behaviour of pituitary neuroendocrine tumours: An exploratory transcriptomic study

Journal of Neuroendocrinology, Volume 38, Issue 4, April 2026.
Abstract The chemokine network in the microenvironment of pituitary neuroendocrine tumours (PitNETs) may modulate tumour biology, aggressiveness, and treatment responses. We aimed to study the role of various chemokines and chemokine receptors in defining PitNET phenotype and clinical outcomes.
Ana Luísa Silva, Sayka Barry, Ana Hipólito, Mariana de Griné Severino, Rita Joaquim, Charlotte Hall, Tiago Oliveira, Dolores López‐Presa, Gonçalo Borrecho, Francisco Tortosa, Ema Nobre, Claudia C. Faria, Márta Korbonits, Pedro Marques   +13 more
wiley   +1 more source

Giant prolactinoma: case report

Objective: To report the clinical case of an adolescent with a giant prolactinoma, diagnosed at the pediatric endocrinology service of a public university hospital in Salvador, Bahia.
Ferreira, Juliane Moreira
core   +1 more source

Serum vaspin and adiponectin levels in patients with prolactinoma

, 2016
Background: Studies investigating serum vaspin and adiponectin levels in patients with prolactinoma are inconclusive. The aim of this study was to evaluate serum vaspin and adiponectin levels in patients with prolactinoma and healthy controls. Methods: A
Ozturk, Gulfer, Arslan, Muyesser Sayki, Ucar, Fatma, Delibasi, Tuncay, Ginis, Zeynep, Erden, Gonul, Erdogan, Serpil, Akyol, Sumeyye   +7 more
core   +1 more source

Giant pubertal prolactinoma: Complete resolution following short term carbegoline treatment [PDF]

, 2016
Prolactinomas are the most common pituitary tumors but rarely seen in adolescent males. There is no indication for surgery both in micro‑ and macro‑adenomas unless an urgent treatment is necessary.
Tuzun, D, Gul, K, Oguz, A, Sahin, M
core   +1 more source

MicroRNA networks in prolactinoma tumorigenesis: a scoping review

Cancer Cell International
Background Prolactinoma is the leading type of pituitary adenoma. Aside from the mass-like effect of prolactinoma, its hormonal effect is the main pathological cause of endocrine dysregulation and infertility.
Sevil Ghaffarzadeh Rad, Fatemeh Nejadi Orang, Mahdi Abdoli Shadbad   +2 more
doaj   +1 more source

Giant prolactinoma with progressive cranial settling and central herniation: a case report

Journal of Medical Case Reports
Background Giant prolactinoma (size > 4 cm) is a rare condition and accounts for less than 1% of pituitary adenomas. In even rarer cases, these lesions may involve craniocervical structures requiring surgical intervention. The present case is the largest
Taha Shahbazi, Soheil Abdollahi Yeganeh, Shiva Borzouei, Mahdi Arjipour   +3 more
doaj   +1 more source