Results 141 to 150 of about 597,091 (260)

Evaluation of proliferative-apoptotic activity in inactive, proliferative, hyperplastic endometria and endometrioid carcinomas

, 2007
Objectives: The role of proliferative and apoptotic mechanisms in various endometrial pathologies and in proliferative and atrophic endometria was assessed by immunohistochemical methods.
Aydin, Nasuhi Engin, Usta, Ufuk, Edali, Mehmet Naci   +2 more
core   +1 more source

CT-based structural phenotypes of thoracic small-joint involvement in psoriatic arthritis. [PDF]

Front Med (Lausanne)
Li T, Zhang Z, Li D, Tong Q, Shen D, Li R.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Recognizing the Benign Behind Worrisome Histology: A Case Report of Proliferative Fasciitis. [PDF]

Reports (MDPI)
Satala CB, Zaharia VV, Gurau AM, Popescu CM, Ciortan RD, Mihalache D.   +5 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

The Divide-Survive Matrix: decoupling proliferative drive from intrinsic survival architecture in oncology. [PDF]

Front Oncol
Heavenor GM.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Immune and cytokine landscape differs between cytopenic and proliferative phenotypes in primary myelofibrosis. [PDF]

Ther Adv Hematol
Lee SH, Wang YH, Chang YS, Wei CH, Yuan CT, Hou HA, Chou WC, Tien HF, Lin CC.   +8 more
europepmc   +1 more source

Timing of neovascular regression in eyes with high-risk proliferative diabetic retinopathy without macular edema treated initially with intravitreous bevacizumab

, 2018
Faiz I Shakarchi,1,2 Ahmed F Shakarchi,3 Shadha A Al-Bayati2 1Department of Ophthalmology, Al-Mustansiriya University – College of Medicine, Baghdad, Iraq; 2Vitreoretinal Department, Ibn Al-Haetham Teaching Eye Hospital, Baghdad, Iraq; 3Baghdad ...
Shakarchi AF, Al-Bayati SA, Shakarchi FI
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source