Results 161 to 170 of about 597,091 (260)

Subtype-Dependent Transcriptional Coupling Between DNMT1 and E2F-Linked Proliferative Programs in Breast Cancer: A Dual-Cohort Transcriptomic Analysis. [PDF]

J Cancer
Xiao P, Xie Y, Niu R, Shan M, Dong Z, Shi Y.   +5 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Advancing Evidence of the Associations between specific Benign Breast Diagnoses and Future Breast Cancer Risk. [PDF]

Cancer Epidemiol Biomarkers Prev
Sattayapiwat O, Weaver DL, Borowsky AD, Keegan THM, Sprague BL, Kerlikowske K, Miglioretti DL.   +6 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Phase-Dependent Changes in Heart Rate Variability During the Menstrual Cycle in Healthy Young Women at a Tertiary Care Center. [PDF]

Cureus
Singh K, Kaur V, Bobbara A.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Determinants of proliferation and involution in infantile hemangioma: macrophage crosstalk, endothelial plasticity, and metabolic rewiring. [PDF]

Front Pediatr
Cai B, Lin Q, Ke R, Chen L, Wan X, Ni X, Shan X, Wang B.   +7 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Cardiac Glycoside 3β-Bufalin Suppresses Cancer Cell Proliferation by Coupling with Na⁺,K⁺-ATPase and Volume-Regulated Anion Channel Within Membrane Microdomains. [PDF]

Int J Mol Sci
Fujii T, Shimizu T, Shimizu Y, Katoh M, Okumura T, Fujii T, Sakai H.   +6 more
europepmc   +1 more source

Proliferative behaviour and cytogenetic changes in human renal-cell carcinoma [PDF]

, 1991
Werner, M., Stief, Christian Georg, Riese, W. de, Azpodien, J., Kirchner, H., Jonas, Udo, Allhoff, E. P., Djamilian, Mohamad H., Schlick, R. W.   +8 more
core   +1 more source