Results 71 to 80 of about 768,209 (306)
Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report
Pediatric Blood &Cancer, EarlyView.ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan +6 more
wiley +1 more source
"Tolerization" of human T-helper cell clones by chronic exposure to alloantigen [PDF]
, 1988 Induction of clonal anergy in T-helper (Th) cells may have a role in regulating immune responses. A model system for studying Th cell tolerization at the clonal level in vitro could be useful for investigating the mechanisms involved.
Brocker, Thomas +6 more
core
Terminal differentiation of adult hippocampal progenitor cells is a step functionally dissociable from proliferation and is controlled by Tis21, Id3 and NeuroD2 [PDF]
, 2017 Cell proliferation and differentiation are interdependent processes. Here, we have asked to what extent the two processes of neural progenitor cell amplification and differentiation are functionally separated.
Daniele Saraulli +9 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
National Journal of Physiology, Pharmacy and Pharmacology, 2020 Background: Cardiac autonomic function in females depends on the fluctuations in the level of endogenous sex hormones during menstrual cycle. Heart rate variability (HRV) is a non-invasive test that helps to assess the function autonomic nervous system ...
Tinju James, Nayana Sunil
doaj +1 more source
A Review of Innovations in Rhegmatogenous Retinal Detachment Surgical Techniques. [PDF]
, 2017 Rhegmatogenous retinal detachment (RRD) requires surgical intervention for its repair. There are variable techniques used for this purpose, and they are all being continuously refined.
Loewenstein, Anat +4 more
core +3 more sources
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Low Ki-67 gene expression in non-neoplastic proliferation of oral mucosal epithelium
Universa Medicina, 2015 BACKGROUND Neoplastic and non-neoplastic oral mucosal growths often have a variety of clinical manifestations according to their biological nature.
Janti Sudiono, Irmawati Hassan
doaj +1 more source
Involvement of Mhc Loci in immune responses that are not Ir-gene-controlled [PDF]
, 1982 Twenty-nine randomly chosen, soluble antigens, many of them highly complex, were used to immunize mice of two strains, C3H and B10.RIII. Lymphnode cells from the immunized mice were restimulated in vitro with the priming antigens and the proliferative ...
C. J. Kreo +28 more
core +1 more source