Cathepsin H as a causal risk factor and therapeutic target in proliferative diabetic retinopathy. [PDF]
Zhou Q +10 more
europepmc +1 more source
ABSTRACT Background Type 1 diabetes (T1D) and overweight/obesity (OW) are chronic conditions impairing health‐related quality of life (HRQoL). While diabetes primarily affects psychosocial domains, OW impacts physical functioning and social stigma. Despite the increasing prevalence of OW among individuals with T1D, their combined effect on HRQoL has ...
Renata Risi +15 more
wiley +1 more source
Efficacy of Ophthalmic Viscosurgical Device-Assisted Vitrectomy for Membrane Removal in Patients With Complex Proliferative Diabetic Retinopathy. [PDF]
Zhang S +4 more
europepmc +1 more source
The effects of intraocular administration of neutralizing antibodies against VEGFA, ANG‐2, or bispecific to these two factors on pathological findings were examined in the oxygen‐induced retinopathy (OIR) mouse model. The antibody to VEGFA or ANG‐2 attenuated oxygen‐induced neovascularization and inflammation, and the bispecific antibody more ...
Hirokazu Oohashi +8 more
wiley +1 more source
Regression Patterns of Neovascularization in Proliferative Diabetic Retinopathy Following Panretinal Photocoagulation - A Prospective, Observational Study. [PDF]
Singh B +5 more
europepmc +1 more source
Candida Drug Resistance in Patients With Diabetic Foot Ulcers: A Systematic Review and Meta‐Analysis
ABSTRACT Diabetic foot ulcers (DFUs) are one of the most serious and common complications that, if not treated properly, can lead to potential damage and even amputation. The aim of this systematic review and meta‐analysis was to assess the drug‐resistant Candida species in DFU.
Mohammad Hossein Ekvan +7 more
wiley +1 more source
LIN28A blocks the EndMT process of high glucose‐induced HRMECs by stabilizing SIRT6 mRNA
LIN28A promotes mRNA stability of SIRT6 to activate the AMPK signaling, thereby inhibiting the EndMT process induced by HG in HRMECs. ABSTRACT Background Diabetic retinopathy (DR) is a microvascular condition resulting from microangiopathy, causing gradual retinal damage and potential blindness.
Xueying Wang +5 more
wiley +1 more source
Combined proteomics and metabolomics analyses revealed molecular signatures associated with proliferative diabetic retinopathy. [PDF]
Cui Y +11 more
europepmc +1 more source
ABSTRACT Aims/Introduction This study aimed to clarify the relationship between glucose metrics measured by continuous glucose monitoring (CGM) and diabetic retinopathy (DR) and albuminuria among Japanese individuals with type 1 diabetes mellitus. Materials and Methods The study included 294 individuals with type 1 diabetes (68.7% women) who underwent ...
Yuichiro Kondo +8 more
wiley +1 more source
Multimodal imaging features of non-proliferative and proliferative diabetic retinopathy based on SD-OCT and fundus autofluorescence. [PDF]
Wang Z +9 more
europepmc +1 more source

