Results 81 to 90 of about 27,228 (223)

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source

Cost‐Effectiveness of Automated Insulin Delivery Systems in Paediatrics, T1D and T2D Adults Across Four Nordic Countries

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study evaluated long‐term cost‐effectiveness of automated insulin delivery (AID) systems versus multiple daily injections (MDI) + CGM in children with type 1 diabetes (T1D), adults with T1D and insulin‐treated individuals with type 2 diabetes (T2D) across Denmark, Finland, Norway and Sweden.
Johan Jendle, Kirsten Nørgaard, Elina Pimiä, Heiko Bratke, Aesha Khan Mirón, Maria‐Eleni Syleouni   +5 more
wiley   +1 more source

Association of SGLT2 Inhibitor With Stroke in Type 2 Diabetes With Diabetic Retinopathy: A Multicenter Electronic Health Record Data Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Diabetic retinopathy (DR) is linked to elevated risks of cerebrovascular diseases. Whether sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) reduce stroke risk in patients with type 2 diabetes (T2D) and DR remains uncertain. Materials and Methods We conducted a retrospective cohort study using the TriNetX Research Network.
Kuo‐En Chen, Po‐Chun Wang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

The technical and practical implementation of fundus photography in equids

Equine Veterinary Education, EarlyView.
Summary Background Fundus photography is an important diagnostic tool in human and veterinary medicine. Advances in research are increasing its accessibility in human medicine. However, there is a lack of studies on modern fundus photography in animals, particularly in horses. Objectives To assess the use of a portable fundus camera developed for human
I. Vierling, B. Wollanke, V. Franzen
wiley   +1 more source

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Cost‐effectiveness analysis comparing real‐time continuous glucose monitoring with self‐monitoring of blood glucose for patients with type 2 diabetes treated with insulin in Japan

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Introduction Real‐time continuous glucose monitoring (rt‐CGM) systems are associated with reductions in glycated hemoglobin (HbA1c) and hypoglycemic events compared with self‐monitoring of blood glucose (SMBG). This analysis aimed to assess the cost‐effectiveness of rt‐CGM compared with SMBG in the management of people with T2D who require ...
Hirotaka Watada, Shiro Tanaka, Jessica Y. Matuoka, Hamza Alshannaq, Richard F. Pollock, Martin Field, Gregory J. Norman   +6 more
wiley   +1 more source

Urinary extracellular vesicle miRNA signature reflects pancreatic islet stress in type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
Urinary ECV miRNAs show a distinct dysregulation signature in T2D with strong diagnostic performance. This signature mirrors molecular changes across pancreatic islets, blood, liver, and adipose tissue, with the strongest concordance in islets, linking it to β‐cell stress. Overall, they represent a non‐invasive, mechanistically informative biomarker of
Md. Zubbair Malik, Mohammed Dashti, Anwar Mohammad, Mohamed Al‐Sayegh, Mohammed Al‐Onaizi, Rasheeba Nizam, Khadija M Dashti, Mohamed Abu‐Farha, Jehad Abubaker, Fahd Al‐Mulla, Hamad Ali   +10 more
wiley   +1 more source

Comparing the Axial Length of Eyes in Patients with Proliferative and Non-proliferative Diabetic Retinopathy

مجله دانشکده پزشکی اصفهان, 2011
Background: Diabetic retinopathy occurs in the retina due to changes in blood vessels. It may cause fluid or blood leakage and fragile vascular bundles which make the sent image to the brain blurry. About half of patients with diabetes mellitus have some
Farhad Fazel, Heshmatollah Ghanbari, Saeed Saghaee   +2 more
doaj  

Plantar fascia thickness in type 1 diabetes mellitus patients: Clinical associations and metabolic correlates

Journal of Diabetes Investigation, EarlyView.
Ultrasound‐measured plantar fascia thickness is associated with microvascular complications and glycemic control in individuals with type 1 diabetes, suggesting PFT as a potential non‐invasive tool for clinical assessment. In addition, improved thickness values were observed in patients using automated insulin delivery systems.
Giulia Casadei, Michele Baldari, Lorenzo Brognara, Enrico Saudelli, Simona Moscatiello, Sara Flamigni, Francesco Traina, Alexandro Paccapelo, Uberto Pagotto, Guido Di Dalmazi   +9 more
wiley   +1 more source

Evaluation of Correlation between Severity of Dry Eye Syndrome and Retinopathy in Patients with Diabetes Mellitus

Armaghane Danesh Bimonthly Journal, 2007
: Introduction & Objective: Diabetes is one of the most common systemic diseases. Dry eye syndrome is one of the eye involvements in diabetic patient. Evaluation of correlation between dry eye syndrome and diabetic retinopathy in patients with insipidus
AR Foroutan, A ASghari, N Afsar, A Vadipour, M Joushghani, N Nilforoushan, AA Nikeghbali, M Mirsamadi   +7 more
doaj