Results 41 to 50 of about 7,344 (158)

M2 Macrophage‐Derived Migrasomes Mediate Ischaemia‐Induced Retinal Neovascularization by Targeting TREM2

Journal of Extracellular Vesicles, Volume 14, Issue 11, November 2025.
M2 macrophages produced and released TREM2‐enriched migrasomes, which were internalized by HRECs through macropinocytosis and phagocytosis. Subsequently, migrasomes up‐regulated pathological retinal angiogenesis and biological functions of HRECs by targeting downstream molecules (BTC, PLA1A, etc).
Bingyan Li, Junyu Chen, Junye Zhu, Haixiang Zhou, Qiuxiang Zhang, Hui Deng, Haipeng Wen, Fan Xu, Fen Tang, Shigeo Yoshida, Yedi Zhou   +10 more
wiley   +1 more source

A Review of Innovations in Rhegmatogenous Retinal Detachment Surgical Techniques

Journal of Ophthalmology, 2017
Rhegmatogenous retinal detachment (RRD) requires surgical intervention for its repair. There are variable techniques used for this purpose, and they are all being continuously refined.
Achia Nemet, Ala Moshiri, Glenn Yiu, Anat Loewenstein, Elad Moisseiev   +4 more
doaj   +1 more source

The Outcomes of Primary 23-gauge Vitrectomy in Retinal Detachment Patients with Grade C Proliferative Vitreoretinopathy Surgery

Boğaziçi Tıp Dergisi, 2019
INTRODUCTION[|]To assess the outcomes of primary vitrectomy in retinal detachment (RD) patients with grade C proliferative vitreoretinopathy (PVR).[¤]METHODS[|]In this study, retrospective, single-surgeon case series were examined.
Hatice Nur Tarakçıoğlu, Burcu Kemer Atik, Abdullah Özkaya   +2 more
doaj   +1 more source

MicroRNA-4516 suppresses proliferative vitreoretinopathy development via negatively regulating OTX1.

PLoS ONE, 2022
Proliferative vitreoretinopathy (PVR) progression is associated with TGF-β2-induced epithelial-mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells.
Shu-I Pao, Le-Tien Lin, Yi-Hao Chen, Ching-Long Chen, Jiann-Torng Chen   +4 more
doaj   +1 more source

Internal closure of a posterior perforation using amniotic membrane: A novel surgical technique

Acta Ophthalmologica, EarlyView.
J. S. Suwandi, B. A. van der Wel, E. H. C. van Dijk, S. S. Manning, M. Manzulli, P. Geeraert, S. van Romunde, K. Faridpooya   +7 more
wiley   +1 more source

Short-Term Total Tamponade with Perfluorocarbon Liquid and Silicone Oil in Complex Rhegmatogenous Retinal Detachment with Severe Proliferative Vitreoretinopathy

Clinical Ophthalmology, 2023
Omar Trabelsi,1 Mejda Bouladi,2 Amel Ouertani,1 Ahmed Trabelsi1 1Clinique Ophtalmologique de Tunis, Tunis, Tunisia; 2Department of Surgery, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, TunisiaCorrespondence: Mejda Bouladi, Faculty ...
Trabelsi O, Bouladi M, Ouertani A, Trabelsi A   +3 more
doaj  

Proteomic Insight into the Role of Exosomes in Proliferative Vitreoretinopathy Development [PDF]

, 2022
Gopa Kumar Gopinadhan Nair, Dimitrios Pollalis, Jonathan D. Wren, Constantin Georgescu, Virginie Sjoelund, Sun Young Lee   +5 more
openalex   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, Volume 103, Issue 7, Page e436-e455, November 2025.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Intravitreal injection of bevacizumab in primary vitrectomy to decrease the rate of retinal redetachment: A randomized pilot study

Journal of Ophthalmic & Vision Research, 2016
Purpose: To evaluate the effect of intravitreal bevacizumab (IVB) as a surgical adjunct in prevention of proliferative vitreoretinopathy (PVR) after retinal detachment surgery. Methods: In this controlled, randomized pilot study, 27 patients with primary
Adib Tousi, Hossein Hasanpour, Masoud Soheilian   +2 more
doaj   +1 more source

Free Radicals in Health and Disease

MedComm, Volume 6, Issue 10, October 2025.
Free radicals have dual roles that can either selectively create oxidative damages to transformed cells in treating proliferative diseases such as cancers and some dermatological disorders or boost the antioxidant system in treating degenerative diseases such as neurodegenerative disorder, joint degeneration, and metabolic conditions.
Xiaofeng Dai, Zizheng Huang, Ruohan Lyu
wiley   +1 more source