Results 41 to 50 of about 7,191 (206)

MicroRNA-4516 suppresses proliferative vitreoretinopathy development via negatively regulating OTX1.

PLoS ONE, 2022
Proliferative vitreoretinopathy (PVR) progression is associated with TGF-β2-induced epithelial-mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells.
Shu-I Pao, Le-Tien Lin, Yi-Hao Chen, Ching-Long Chen, Jiann-Torng Chen   +4 more
doaj   +1 more source

Prediction of late results of surgical treatment of traumatic retina detachment in eye injury of multiple origin

Российский офтальмологический журнал, 2023
Purpose. To evaluate the possibility of predicting the anatomical and functional results of surgical treatment of traumatic retinal detachment (RD) in trauma of various geneses, taking into account the clinical picture and the severity of the ...
N. L. Leparskaya
doaj   +1 more source

Comparison of treatment routine using aflibercept: Strict vs. relaxed retreatment regimen (TOLERANT study)—A non‐inferiority, randomized controlled trial

Acta Ophthalmologica, Volume 103, Issue 6, Page e385-e393, September 2025.
Abstract Purpose This trial evaluated the noninferiority of a relaxed compared to a strict treat‐and‐extend treatment strategy in patients with neovascular Age‐related macular degeneration (AMD). Methods Multicenter, randomized, controlled, phase IV, non‐inferiority clinical trial.
Damian Jaggi, Lieselotte E. Berger, Sandrine Zweifel, Matthias D. Becker, Stephan Michels, Odile Stalder, Joel‐Benjamin Lincke, Oussama Habra, Sebastian Wolf, Martin S. Zinkernagel   +9 more
wiley   +1 more source

A Review of Innovations in Rhegmatogenous Retinal Detachment Surgical Techniques

Journal of Ophthalmology, 2017
Rhegmatogenous retinal detachment (RRD) requires surgical intervention for its repair. There are variable techniques used for this purpose, and they are all being continuously refined.
Achia Nemet, Ala Moshiri, Glenn Yiu, Anat Loewenstein, Elad Moisseiev   +4 more
doaj   +1 more source

The Outcomes of Primary 23-gauge Vitrectomy in Retinal Detachment Patients with Grade C Proliferative Vitreoretinopathy Surgery

Boğaziçi Tıp Dergisi, 2019
INTRODUCTION[|]To assess the outcomes of primary vitrectomy in retinal detachment (RD) patients with grade C proliferative vitreoretinopathy (PVR).[¤]METHODS[|]In this study, retrospective, single-surgeon case series were examined.
Hatice Nur Tarakçıoğlu, Burcu Kemer Atik, Abdullah Özkaya   +2 more
doaj   +1 more source

Post‐Translational Modifications in Cilia and Ciliopathies

Advanced Science, Volume 12, Issue 31, August 21, 2025.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source

Short-Term Total Tamponade with Perfluorocarbon Liquid and Silicone Oil in Complex Rhegmatogenous Retinal Detachment with Severe Proliferative Vitreoretinopathy

Clinical Ophthalmology, 2023
Omar Trabelsi,1 Mejda Bouladi,2 Amel Ouertani,1 Ahmed Trabelsi1 1Clinique Ophtalmologique de Tunis, Tunis, Tunisia; 2Department of Surgery, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, TunisiaCorrespondence: Mejda Bouladi, Faculty ...
Trabelsi O, Bouladi M, Ouertani A, Trabelsi A   +3 more
doaj  

Levodopa‐Responsive Dystonia Secondary to CTNNB1 Neurodevelopmental Disorder

Movement Disorders Clinical Practice, EarlyView.
Hanin Algethami, Wei Kang Lim, David Chitayat, Ingrid Tein, Alfonso Fasano, Carolina Gorodetsky   +5 more
wiley   +1 more source

Diabetic retinopathy and Alzheimer's disease: Convergence of the unfolded protein response in neurodegeneration

Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract Diabetic retinopathy (DR) and Alzheimer's disease (AD) are progressive neurodegenerative disorders affecting the eye and the brain, respectively. Despite targeting different organs, they share common molecular mechanisms. A central process connecting these conditions is the unfolded protein response (UPR), which maintains protein homeostasis ...
Adrián G. Palacios, Sarah X. Zhang, Mónica L. Acosta   +2 more
wiley   +1 more source

Intravitreal injection of bevacizumab in primary vitrectomy to decrease the rate of retinal redetachment: A randomized pilot study

Journal of Ophthalmic & Vision Research, 2016
Purpose: To evaluate the effect of intravitreal bevacizumab (IVB) as a surgical adjunct in prevention of proliferative vitreoretinopathy (PVR) after retinal detachment surgery. Methods: In this controlled, randomized pilot study, 27 patients with primary
Adib Tousi, Hossein Hasanpour, Masoud Soheilian   +2 more
doaj   +1 more source