Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment [PDF]
, 2018 Purpose: To determine 1) which components of retinal function are impaired after rhegmatogenous retinal detachment, 2) which outer retinal pathways (rod- or cone-driven) are more severely affected, and 3) whether there is concomitant inner retinal ...
Apte, Rajendra +3 more
core +3 more sources
Case Reports in Ophthalmology, 2018 Purpose: Proliferative vitreoretinopathy is a well-known cause of failure of retinal detachment surgery. The purpose of this case report is to illustrate the clinical occurrence and histopathology of a horizontal subretinal band (“clothesline ...
Karen R. Brown +3 more
doaj +1 more source
Future Pharmacology, 2023 In this study, we retrospectively reviewed the outcomes of patients treated with one or more series of intravitreal methotrexate (MTX) injections as a surgical adjunct for the prevention of recurrent rhegmatogenous retinal detachment (RRD) related to ...
Tessnim R. Ahmad, Jay M. Stewart
doaj +1 more source
Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?
Acta Ophthalmologica, EarlyView.Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs +12 more
wiley +1 more source
Human cytokines activate JAK–STAT signaling pathway in porcine ocular tissue [PDF]
, 2015 Background: The JAK/STAT (Janus Tyrosine Kinase, Signal Transducers and Activators of Transcription) pathway is associated with cytokine or growth factor receptors and it is critical for growth control, developmental regulation and homeostasis.
Barteneva, Natasha S +8 more
core +1 more source
MicroRNA-4516 suppresses proliferative vitreoretinopathy development via negatively regulating OTX1.
PLoS ONE, 2022 Proliferative vitreoretinopathy (PVR) progression is associated with TGF-β2-induced epithelial-mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells.
Shu-I Pao +4 more
doaj +1 more source
Ozurdex(R) (a slow-release dexamethasone implant) in proliferative vitreoretinopathy: study protocol for a randomised controlled trial [PDF]
, 2013 Proliferative vitreoretinopathy (PVR) is the commonest cause of late anatomical failure in rhegmatogenous retinal detachment. Visual and anatomical outcomes remain poor despite advances in vitreoretinal surgical techniques with reported primary failure ...
Banerjee, PJ, Bunce, C, Charteris, DG
core
The effect of a preoperative subconjuntival injection of dexamethasone on blood-retinal barrier breakdown following scleral buckling retinal detachment surgery: a prospective randomized placebo-controlled double blind clinical trial [PDF]
, 2010 Background: Blood-retinal barrier breakdown secondary to retinal detachment and retinal detachment repair is a factor in the pathogenesis of proliferative vitreoretinopathy (PVR). We wished to investigate whether an estimated 700 to 1000 ng/ml subretinal
Bali, E. (Ernesto) +5 more
core +2 more sources
Acta Ophthalmologica, EarlyView.Abstract Purpose This systematic review aims to evaluate and synthesize the existing literature on the interventions used for submacular haemorrhage (SMH), highlighting the controversies and differences in clinical practice. Method A systematic review was conducted following the PRISMA guidelines.
Salvador Pastor‐Idoate +6 more
wiley +1 more source
Proliferative vitreoretinopathy
Zdravniški Vestnik, 2005 Background: Proliferative vitreoretinopathy (PVR) is a disease characterized by formation of membranes on both surfaces of the retina and vitreous base. PVR is a wound healing response which is inadequate and uncontrolled in the eye. Identifying the risk
Mojca Globočnik-Petrovič +1 more
doaj