Results 51 to 60 of about 10,443 (200)

Techniques for subretinal injections in animals

Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

Intravitreal injection of bevacizumab in primary vitrectomy to decrease the rate of retinal redetachment: A randomized pilot study

Journal of Ophthalmic & Vision Research, 2016
Purpose: To evaluate the effect of intravitreal bevacizumab (IVB) as a surgical adjunct in prevention of proliferative vitreoretinopathy (PVR) after retinal detachment surgery. Methods: In this controlled, randomized pilot study, 27 patients with primary
Adib Tousi, Hossein Hasanpour, Masoud Soheilian   +2 more
doaj   +1 more source

A Retrospective Clinical Study of the Etiology and Post-operative Visual Outcome of Rhegmatogenous Retinal Detachment [PDF]

Journal of Clinical and Diagnostic Research, 2014
Aim: To study the etiology of rhegmatogenous retinal detachment and visual outcome after retinal detachment surgery. Materials and methods: Retrospective study conducted at the tertiary eye care hospital over a period of one year.
Achyut N Pandey, Anil Kakde
doaj   +1 more source

Comparison of treatment routine using aflibercept: Strict vs. relaxed retreatment regimen (TOLERANT study)—A non‐inferiority, randomized controlled trial

Acta Ophthalmologica, Volume 103, Issue 6, Page e385-e393, September 2025.
Abstract Purpose This trial evaluated the noninferiority of a relaxed compared to a strict treat‐and‐extend treatment strategy in patients with neovascular Age‐related macular degeneration (AMD). Methods Multicenter, randomized, controlled, phase IV, non‐inferiority clinical trial.
Damian Jaggi, Lieselotte E. Berger, Sandrine Zweifel, Matthias D. Becker, Stephan Michels, Odile Stalder, Joel‐Benjamin Lincke, Oussama Habra, Sebastian Wolf, Martin S. Zinkernagel   +9 more
wiley   +1 more source

Diabetic retinopathy and Alzheimer's disease: Convergence of the unfolded protein response in neurodegeneration

Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract Diabetic retinopathy (DR) and Alzheimer's disease (AD) are progressive neurodegenerative disorders affecting the eye and the brain, respectively. Despite targeting different organs, they share common molecular mechanisms. A central process connecting these conditions is the unfolded protein response (UPR), which maintains protein homeostasis ...
Adrián G. Palacios, Sarah X. Zhang, Mónica L. Acosta   +2 more
wiley   +1 more source

The Outcomes of Primary 23-gauge Vitrectomy in Retinal Detachment Patients with Grade C Proliferative Vitreoretinopathy Surgery

Boğaziçi Tıp Dergisi, 2019
INTRODUCTION[|]To assess the outcomes of primary vitrectomy in retinal detachment (RD) patients with grade C proliferative vitreoretinopathy (PVR).[¤]METHODS[|]In this study, retrospective, single-surgeon case series were examined.
Hatice Nur Tarakçıoğlu, Burcu Kemer Atik, Abdullah Özkaya   +2 more
doaj   +1 more source

Chorioretinal Coloboma Complications: Retinal Detachment and Choroidal Neovascular Membrane [PDF]

, 2017
PURPOSE: To report the chorioretinal coloboma, and its association with increased risk of retinal detachment (RD) and choroidal neovascularization (CNV).
Abbey, Ashkan M., Capone Jr., Antonio, Drenser, Kimberly A., Hussain, Rehan M., Shah, Ankoor R., Trese, Michael T.   +5 more
core   +3 more sources

The dark sides of the GPCR tree ‐ research progress on understudied GPCRs

British Journal of Pharmacology, Volume 182, Issue 14, Page 3109-3134, July 2025.
Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf, Laura J. Humphrys, Sandra Berndt, Antonella Di Pizio, Juliane Lehmann, Ines Liebscher, Alessandro Nicoli, Masha Y. Niv, Lior Peri, Hannes Schihada, Gunnar Schulte   +10 more
wiley   +1 more source

Anterior proliferative vitreoretinopathy in a patient with Coats disease [PDF]

International Journal of Ophthalmology, 2018
Letter to the ...
Satoru Kase, Shohei Mori, Kousuke Noda, Susumu Ishida   +3 more
doaj   +1 more source

Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]

, 2012
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Aisenbrey, Alcazar, Alge, Bhutto, Bodaghi, Burke, Campochiaro, Christoph Szober, Chu, Claudia Alge-Priglinger, Clegg, Cornelia Deeg, Deeg, Deeg, Deeg, Deeg, Deeg, Degroote, Doherty, Dunn, Eberhardt, Ehrenhofer, Greer, Gullapalli, Gundersen, Ham, Hamel, Hauck, Hauck, Hauck, Hauck, Ho, Huang, Karl, Kerstin Euler, Kristina Fröhlich, Li, Limb, Machemer, Marius Ueffing, McBee, Milyushina, Mochizuki, Muramatsu, Nagai, Parker, Philp, Rizzolo, Rotilio, Singer, Stefanie Hauck, Strauss, Vacanti, Wolf, Wu   +54 more
core   +3 more sources