Results 51 to 60 of about 10,365 (241)

Clinicopathologic Correlation of a Subretinal Proliferative Vitreoretinopathy Band in a Patient with Chronic Recurrent Retinal Detachment

Case Reports in Ophthalmology, 2018
Purpose: Proliferative vitreoretinopathy is a well-known cause of failure of retinal detachment surgery. The purpose of this case report is to illustrate the clinical occurrence and histopathology of a horizontal subretinal band (“clothesline ...
Karen R. Brown, Sander R. Dubovy, Nidhi Relhan, Harry W. Flynn Jr.   +3 more
doaj   +1 more source

Tolerability and Efficacy of Multiple Series of Intravitreal Methotrexate Injections for Complex Retinal Detachment Associated with Proliferative Vitreoretinopathy

Future Pharmacology, 2023
In this study, we retrospectively reviewed the outcomes of patients treated with one or more series of intravitreal methotrexate (MTX) injections as a surgical adjunct for the prevention of recurrent rhegmatogenous retinal detachment (RRD) related to ...
Tessnim R. Ahmad, Jay M. Stewart
doaj   +1 more source

Thrombin Generation in Vitreous and Subretinal Fluid of Patients with Retinal Detachment [PDF]

, 2018
Purpose: To measure prothrombin fragments (F1+2) and thrombin-antithrombin complex (TAT) in vitreous and subretinal fluid (SRF) of rhegmatogenous retinal detachment (RRD) patients and to validate and further specify our earlier finding of increased ...
Bastiaans, J. (Jeroen), Kluft, C. (Cornelis), Meurs, J.C. (Jan) van, Mulder, V.C. (Verena), van Leuven, C.J.M. (Cornelis J.M.)   +4 more
core   +1 more source

Comparison of treatment routine using aflibercept: Strict vs. relaxed retreatment regimen (TOLERANT study)—A non‐inferiority, randomized controlled trial

Acta Ophthalmologica, EarlyView.
Abstract Purpose This trial evaluated the noninferiority of a relaxed compared to a strict treat‐and‐extend treatment strategy in patients with neovascular Age‐related macular degeneration (AMD). Methods Multicenter, randomized, controlled, phase IV, non‐inferiority clinical trial.
Damian Jaggi, Lieselotte E. Berger, Sandrine Zweifel, Matthias D. Becker, Stephan Michels, Odile Stalder, Joel‐Benjamin Lincke, Oussama Habra, Sebastian Wolf, Martin S. Zinkernagel   +9 more
wiley   +1 more source

Изучение антипролиферативного эффекта интравитреального имплантата при хирургическом лечении пролиферативной витреоретинопатии [PDF]

, 2015
СТЕКЛОВИДНОЕ ТЕЛОВИТРЕОРЕТИНОПАТИЯ ПРОЛИФЕРАТИВНАЯ /ХИРХИТОЗАНФТОРУРАЦИЛМОРФОЛОГИЧЕСКИЕ ИССЛЕДОВАНИЯПОСЛЕОПЕРАЦИОННЫЙ ...
Байырханова, А. О., Ботабекова, Т. К., Семёнова, Ю. М.   +2 more
core   +1 more source

Techniques for subretinal injections in animals

Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

MicroRNA-4516 suppresses proliferative vitreoretinopathy development via negatively regulating OTX1.

PLoS ONE, 2022
Proliferative vitreoretinopathy (PVR) progression is associated with TGF-β2-induced epithelial-mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells.
Shu-I Pao, Le-Tien Lin, Yi-Hao Chen, Ching-Long Chen, Jiann-Torng Chen   +4 more
doaj   +1 more source

Autologous peripheral retinal pigment epithelium translocation in patients with subfoveal neovascular membranes [PDF]

, 2004
AIM: To evaluate the possibility of translocating autologous peripheral retinal pigment epithelial (RPE) cells and enhance their adhesion to improve functional outcome after choroidal neovascular membrane ...
Baarsma, G.S. (Seerp), Boks, T., Hagen, P.M. (Martin) van, Hofland, L.J. (Leo), Kuijpers, R.W.A.M. (Robert), Meurs, J.C. (Jan) van, Mooy, C.M. (Cornelia), Stalmans, P., ter Averst, E.   +8 more
core   +3 more sources

The dark sides of the GPCR tree ‐ research progress on understudied GPCRs

British Journal of Pharmacology, Volume 182, Issue 14, Page 3109-3134, July 2025.
Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf, Laura J. Humphrys, Sandra Berndt, Antonella Di Pizio, Juliane Lehmann, Ines Liebscher, Alessandro Nicoli, Masha Y. Niv, Lior Peri, Hannes Schihada, Gunnar Schulte   +10 more
wiley   +1 more source

Proliferative vitreoretinopathy

Zdravniški Vestnik, 2005
Background: Proliferative vitreoretinopathy (PVR) is a disease characterized by formation of membranes on both surfaces of the retina and vitreous base. PVR is a wound healing response which is inadequate and uncontrolled in the eye. Identifying the risk
Mojca Globočnik-Petrovič, Andrejka Preskar   +1 more
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