Results 121 to 130 of about 329,298 (293)

cis-4-pyrrolidin-1-yl-1-proline: A highly stereoselective organocatalyst for the direct aldol reaction

, 2006
Modification of the pyrrolidinyl backbone of proline has not been quite successful for improving the catalytic efficiency and enantioselectivity. In this study, cis substitutions on the C4 position of proline with nitrogen-containing groups were found to
Wang, Y, Sun, J, Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Peoples R China., Wei, SY, Sun, J   +3 more
core  

Funnel plot used to explore the potential for publication bias in the meta-analysis of 33 series for the effect of isoleucine–proline–proline/valine–proline–proline on systolic blood pressure in Japanese subjects.

, 2015
Series numbers are those indicated in Table 2. IPP: isoleucine–proline–proline. SBP: systolic blood pressure. VPP: valine–proline–proline.
Aurelie Chanson-Rolle (758940), Toshimitsu Hamasaki (542228), Veronique Braesco (758943), François Aubin (742505), Masafumi Kitakaze (213326)   +4 more
core   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

Advanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan, Yan Zheng, Yue Lan, Zhuo Cheng, Siya Wang, Changqing Li, Yanqiu Wang, Minghan Liu   +7 more
wiley   +1 more source

Morphological, physiological, and biochemical responses of three different soybean (Glycine max L.) varieties under salinity stress conditions

Frontiers in Plant Science
Salinity is one of the most detrimental factors for the growth performance and productivity of crops worldwide. Therefore, understanding crop responses or growth potentials and their effectiveness in salinity mitigation is highly important for the ...
Desilal Kokebie, Abiyu Enyew, Getinet Masresha, Tarekegn Fentie, Emebet Mulat   +4 more
doaj   +1 more source

Synthesis of a Novel cis-Proline-Derived Cyclic Type VI β-Turn Mimic via Ring-Closing Metathesis^†

, 2016
A cis-proline derived cyclic mimic of a type VI β-turn is synthesized via a ring-closing metathesis reaction. The solution NMR conformational study indicates that the major conformer of the cyclic peptide adopts a type VIa β-turn in CDCl3 and a type VIb ...
Anima Boruah (2722039), Javed Iqbal (2121922), I. Nageshwar Rao (3032109), S. Kiran Kumar (2705278), Jyoti Prokash Nandy (3029643), A. C. Kunwar (1944397)   +5 more
core   +1 more source

Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions

Advanced Science, EarlyView.
This study uncovers a tri‐directional interplay among cells, hydrogels, and their nascent extracellular matrix. Hydrogel norbornene modification alters CD44‐mediated cell–hydrogel interactions, which shape nascent matrix deposition, composition, and spatial organization.
Joshua Y. Liu, Ziqian Yang, Arina E. Velieva, Eleanor M. Plaster, Mingyue Fan, Donia W. Ahmed, Avinava Roy, Pamela Duran, Pamela Panovich, Alexandra S. Piotrowski‐Daspit, Carlos A. Aguilar, Megan L. Killian, Claudia Loebel   +12 more
wiley   +1 more source

Proline-catalyzed asymmetric reactions

, 2002
Several strategies are available for enantioselective catalysis, including heterogeneous catalysis, Brønsted or Lewis acid and base catalysis, homogeneous transition-metal catalysis, and biocatalysis.
List, B.
core   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

N-acetyl proline-glycine-proline: implications for neurological disorders

Neural Regeneration Research, 2016
Jeff W Hill, Edwin M Nemoto
doaj   +1 more source